Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)

• Catalog number
  MBS626298
• Price
  Please ask
• Size
  50ug

• Alternative name1
  Anti-Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)
• Alternative name2
  Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)
• Alternative name3
  Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)
• Alternative name4
  Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha
• Alternative name5
  Anti -Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)
• Other names
  granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GMR-alpha; GMCSFR-alpha; CD116 antigen; OTTHUMP00000014504; OTTHUMP00000014505; OTTHUMP00000014506; OTTHUMP00000014507; OTTHUMP00000014508; OTTHUMP00000014917; OTTHUMP00000014918; OTTHUMP00000014919; OTTHUMP00000014920; GM-CSF receptor alpha subunit; colony stimulating factor 2 receptor alpha subunit; granulocyte-macrophage colony-stimulating factor receptor alpha chain; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); CDw116
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  CSF2RA; CSF2RA; GMR; CD116; CSF2R; CDw116; CSF2RX; CSF2RY; GMCSFR; CSF2RAX; CSF2RAY; MGC3848; MGC4838; GM-CSF-R-alpha; CSF2R; CSF2RY
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  N/A
• Clone
  Polyclonal antibody
• Host organism
  Host: Mouse; Source: Human
• Species reactivity
  Human
• Specificity and cross reactivity
  Recognizes human CSF2RA.
• Purification method
  Purified.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store at 4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap.
• Tested for
  Western Blot (WB), Flow Cytometry (FC/FACS)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  The Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY) is a α- or alpha protein sometimes glycoprotein present in blood. Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Gene
  Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.

• Gene target
  Granulocyte   Macrophage   Colony   Stimulating   Factor   Receptor   alpha   Granulocyte-macrophage   Colony-stimulating   Factor   Receptor   Subunit   alpha   CSF2RA   GM-CSF-R-alpha   GMCSFR-alpha   GMR-alpha   CDw116   CD116   CSF2R   CSF2RY  
• Gene symbol
  CSF2RA, CSF2, PPP1R3A, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R, CSF1, CSF3
• Short name
  Granulocyte Macrophage Colony Stimulating Factor Receptor, alpha (Granulocyte-macrophage Colony-stimulating Factor Receptor Subunit alpha, CSF2RA, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CDw116, CD116, CSF2R, CSF2RY)
• Alternative name
  Granulocyte Macrophage Colony Stimulating Factor Receptor, a (Granulocyte-macrophage Colony-stimulating Factor Receptor functionnal sequence a, colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage), GM-CSF-R-a, GMCSFR-a, GMR-a, CDw116, CD116, CSF2R, CSF2RY)
• Alternative to gene target
  colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
• Tissue
  granulocyte

Gene info

• Identity
  HGNC:2435
• Gene
  CSF2RA
• Long gene name
  colony stimulating factor 2 receptor subunit alpha
• Synonyms gene
  • CSF2R
• Synonyms gene name
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
• Synonyms
  • CD116
  • alphaGMR
• Synonyms name
  • alpha-GM-CSF receptor
• GenBank acession
  • M64445
• Locus
  Xp22.32 and Yp11.3
• Discovery year
  1990-07-03
• Entrez gene record
  1438
• Pubmed identfication
  • 1702217
• Classification
  • CD molecules
  • Pseudoautosomal region 1
• VEGA ID
  OTTHUMG00000012533
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_186

Gene info

• Identity
  HGNC:2434
• Gene
  CSF2
• Long gene name
  colony stimulating factor 2
• Synonyms gene name
  • colony stimulating factor 2 (granulocyte-macrophage)
• Synonyms
  • GM-CSF
  • GMCSF
• Synonyms name
  • sargramostim
  • molgramostim
  • granulocyte-macrophage colony stimulating factor
• GenBank acession
  • M11734
• Locus
  5q31.1
• Discovery year
  2001-06-22
• Entrez gene record
  1437
• Pubmed identfication
  • 3898082
  • 2999978
• RefSeq identity
  • NM_000758
• VEGA ID
  OTTHUMG00000059637

Gene info

• Identity
  HGNC:9291
• Gene
  PPP1R3A
• Long gene name
  protein phosphatase 1 regulatory subunit 3A
• Synonyms gene
  • PPP1R3
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle)
  • protein phosphatase 1, regulatory (inhibitor) subunit 3A
  • protein phosphatase 1, regulatory subunit 3A
• Synonyms
  • GM
• Synonyms name
  • glycogen-associated regulatory subunit of protein phosphatase-1
  • protein phosphatase 1 regulatory subunit GM
• GenBank acession
  • AF024578
• Locus
  7q31.1
• Discovery year
  1993-01-22
• Entrez gene record
  5506
• Pubmed identfication
  • 7926294
• RefSeq identity
  • NM_002711
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000156944

Gene info

• Identity
  HGNC:10447
• Gene
  RRAS
• Long gene name
  RAS related
• Synonyms gene name
  • related RAS viral (r-ras) oncogene homolog
• Synonyms
  • R-Ras
• Synonyms name
  • Oncogene RRAS
• Locus
  19q13.33
• Discovery year
  2001-06-22
• Entrez gene record
  6237
• Pubmed identfication
  • 3098437
• RefSeq identity
  • NM_006270
• Classification
  • RAS type GTPase family
• VEGA ID
  OTTHUMG00000183247

Gene info

• Identity
  HGNC:18295
• Gene
  DAD1P1
• Long gene name
  defender against cell death 1 pseudogene 1
• Synonyms gene
  • DAD1L
• Synonyms gene name
  • defender against cell death 1-like
• Synonyms
  • DAD-R
• Locus
  12p12.1
• Discovery year
  2007-07-26
• Entrez gene record
  56286
• Pubmed identfication
  • 10812081
  • 11912161
• RefSeq identity
  • NR_024064

Gene info

• Identity
  HGNC:5047
• Gene
  HNRNPR
• Long gene name
  heterogeneous nuclear ribonucleoprotein R
• Synonyms gene
  • HNRPR
• Synonyms
  • hnRNP-R
• GenBank acession
  • AF000364
• Locus
  1p36.12
• Discovery year
  1999-06-11
• Entrez gene record
  10236
• Pubmed identfication
  • 9421497
• RefSeq identity
  • NM_005826
• Classification
  • Heterogeneous nuclear ribonucleoproteins
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000003224

Gene info

• Identity
  HGNC:2046
• Gene
  CLDN4
• Long gene name
  claudin 4
• Synonyms gene
  • CPETR
  • CPETR1
• Synonyms
  • CPE-R
  • WBSCR8
  • hCPE-R
• Synonyms name
  • Clostridium perfringens enterotoxin receptor 1
  • Williams-Beuren syndrome chromosomal region 8 protein
• GenBank acession
  • AB000712
• Locus
  7q11.23
• Discovery year
  1998-04-22
• Entrez gene record
  1364
• Pubmed identfication
  • 9334247
  • 9892664
• RefSeq identity
  • NM_001305
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000023425

Gene info

• Identity
  HGNC:6929
• Gene
  MC1R
• Long gene name
  melanocortin 1 receptor
• Synonyms gene name
  • melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
• Synonyms
  • MSH-R
• Synonyms name
  • alpha melanocyte stimulating hormone receptor
• Locus
  16q24.3
• Discovery year
  1993-07-27
• Entrez gene record
  4157
• Pubmed identfication
  • 8458079
• RefSeq identity
  • NM_002386
• Classification
  • Melanocortin receptors
• VEGA ID
  OTTHUMG00000171163

Gene info

• Identity
  HGNC:2432
• Gene
  CSF1
• Long gene name
  colony stimulating factor 1
• Synonyms gene name
  • colony stimulating factor 1 (macrophage)
• Synonyms
  • M-CSF
  • MCSF
  • MGC31930
• Synonyms name
  • macrophage colony stimulating factor 1
• GenBank acession
  • BC021117
• Locus
  1p13.3
• Discovery year
  1986-01-01
• Entrez gene record
  1435
• Pubmed identfication
  • 1540160
• RefSeq identity
  • NM_000757
• VEGA ID
  OTTHUMG00000011646

Gene info

• Identity
  HGNC:2438
• Gene
  CSF3
• Long gene name
  colony stimulating factor 3
• Synonyms gene
  • GCSF
  • G-CSF
  • C17orf33
• Synonyms gene name
  • chromosome 17 open reading frame 33
  • colony stimulating factor 3 (granulocyte)
• Synonyms
  • MGC45931
• Synonyms name
  • granulocyte colony stimulating factor
  • pluripoietin
  • filgrastim
  • lenograstim
• Locus
  17q21.1
• Discovery year
  2001-06-22
• Entrez gene record
  1440
• Pubmed identfication
  • 3499671
  • 3501046
• RefSeq identity
  • NM_172220
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000133247

MeSH Data

• Name
  Colony-Forming Units Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of stem cells by assaying their activity.
• Tree numbers
  • E01.370.225.500.383
  • E05.200.500.383
  • E05.242.383
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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