FXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Nuclear Receptor Subfamily 1 Group H Member 4, NR1H4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14)
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Catalog numberMBS618940
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PricePlease ask
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Size5x0.1 mL
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Products_typeAntibody
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Products_short_name[FXR]
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Products_name_syn[Anti -FXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Nuclear Receptor Subfamily 1 Group H Member 4, NR1H4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14)]
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Other_names[FXR; FXR; farnesoid X-activated receptor; farnesoid X-activated receptor]
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Other_gene_names[fxr; fxr; fxr]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificitySpecies Crossreactivity: Human. Other species have not been tested.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormSupplied as a liquid in Tris-glycine, 150mM sodium chloride,, pH 7.2, 0.05% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolNR1H4, BFAR, ADRB2, AP1AR, GPBAR1, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
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Short nameFXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Receptor Subfamily 1 Group H Member 4, NR1H4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14)
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HostRabbit
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Alternative nameFXR (Farnesoid X-activated Receptor, Bile Acid Receptor, BAR, HRR-1, Nuclear Receptor Subfamily 1 family H Member 4, nuclear receptor subfamily 1, group H, member 4, Retinoid X Receptor-interacting Protein 14, RXR-interacting Protein 14, RIP14)
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Alternative to gene targetnuclear receptor subfamily 1, group H, member 4, BAR and FXR and HRR-1 and HRR1 and RIP14, NR1H4 and IDBG-52872 and ENSG00000012504 and 9971, chenodeoxycholic acid binding, nuclei, Nr1h4 and IDBG-184281 and ENSMUSG00000047638 and 20186, BT.48865 and IDBG-636894 and ENSBTAG00000013596 and 540528
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Gene info
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Identity
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Gene
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Long gene namenuclear receptor subfamily 1 group H member 4
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Synonyms gene name
- nuclear receptor subfamily 1, group H, member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-09-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nuclear receptor subfamily 1 group H
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namebifunctional apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sterile alpha motif domain containing
- Ring finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadrenoceptor beta 2
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Synonyms gene
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Synonyms gene name
- adrenergic, beta-2-, receptor, surface
- adrenoceptor beta 2, surface
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-09-10
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Entrez gene record
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RefSeq identity
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Classification
- Adrenoceptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameadaptor related protein complex 1 associated regulatory protein
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Synonyms gene
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Synonyms gene name
- chromosome 4 open reading frame 16
- adaptor-related protein complex 1 associated regulatory protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-09-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein-coupled bile acid receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-01-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein-coupled bile acid receptor
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
