Human Bile acid receptor (NR1H4)
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Catalog number
CSB-EP839406HU-1MG
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Price
Please ask
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Size
1MG
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Description
Recombinant Human Bile acid receptor(NR1H4) expressed in E.coli
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Specifications
Uniprot ID: Q96RI1; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 1-476aa; Sequence information: Full Length of Isoform 3 ; Tag: N-terminal 6xHis-SUMO-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
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Additional_information
MW: 70.7 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
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Storage_and_shipping
Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
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Notes
For research use only.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NR1H4
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Short name
Bile acid receptor (NR1H4)
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Species
Human, Humans
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Alternative name
H. sapiens Bile acid receptor (nuclear receptor subfamily 1, group H, member 4)
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Alternative to gene target
nuclear receptor subfamily 1, group H, member 4, BAR and FXR and HRR-1 and HRR1 and RIP14, NR1H4 and IDBG-52872 and ENSG00000012504 and 9971, chenodeoxycholic acid binding, nuclei, Nr1h4 and IDBG-184281 and ENSMUSG00000047638 and 20186, BT.48865 and IDBG-636894 and ENSBTAG00000013596 and 540528
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Gene info
Product images
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