Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)

  • Catalog number
    MBS622235
  • Price
    Please ask
  • Size
    5x0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [Fibroblast Growth Factor Receptor Substrate 3]
  • Products_name_syn
    [Anti -Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)]
  • Other_names
    [fibroblast growth factor receptor substrate 3; Fibroblast growth factor receptor substrate 3; fibroblast growth factor receptor substrate 3; FRS2-beta; FGFR substrate 3; OTTHUMP00000016383; FGFR-signaling adaptor SNT2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); fibroblast growth factor receptor substrate 3; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2]
  • Other_gene_names
    [FRS3; FRS3; SNT2; FRS2B; SNT-2; FRS2beta; MGC17167]
  • Clonality
    Polyclonal
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes human FRS3/FRS2b. Species crossreactivity: mouse, rat.
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a liquid in PBS, 0.05% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    Western Blot (WB)
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
  • Gene target
  • Gene symbol
    FRS3, SNTB1, FRS2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2
  • Short name
    Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor 2, SNT-2)
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)
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