Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)
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Catalog numberMBS622235
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PricePlease ask
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[Fibroblast Growth Factor Receptor Substrate 3]
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Products_name_syn[Anti -Fibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)]
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Other_names[fibroblast growth factor receptor substrate 3; Fibroblast growth factor receptor substrate 3; fibroblast growth factor receptor substrate 3; FRS2-beta; FGFR substrate 3; OTTHUMP00000016383; FGFR-signaling adaptor SNT2; suc1-associated neurotrophic factor target 2 (FGFR signalling adaptor); fibroblast growth factor receptor substrate 3; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2]
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Other_gene_names[FRS3; FRS3; SNT2; FRS2B; SNT-2; FRS2beta; MGC17167]
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ClonalityPolyclonal
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ReactivityHuman, Mouse, Rat
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SpecificityRecognizes human FRS3/FRS2b. Species crossreactivity: mouse, rat.
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PurityAffinity Purified Purified by immunoaffinity chromatography.
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FormSupplied as a liquid in PBS, 0.05% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB)
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
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Gene target
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Gene symbolFRS3, SNTB1, FRS2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
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Short nameFibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor 2, SNT-2)
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HostRabbit
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IsotypeIgG
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Alternative nameFibroblast Growth Factor Receptor Substrate 3 (FRS3, FGFR Substrate 3, FGFR-signaling adaptor SNT2, Suc1-associated Neurotrophic Factor Target 2, SNT-2)
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Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor receptor substrate 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-05-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesyntrophin beta 1
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Synonyms gene
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Synonyms gene name
- syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- Pleckstrin homology domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor receptor substrate 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-05-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR329 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namekeratin associated protein 13-2
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-21
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Entrez gene record
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Pubmed identfication
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Classification
- Keratin associated proteins
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VEGA ID