Complement C5, Human

• Catalog number
  MBS632559
• Price
  Please ask
• Size
  5x0.05 mg

• Products_type
  Antibody
• Products_short_name
  [Complement C5]
• Products_name_syn
  [Anti -Complement C5, Human]
• Other_names
  [complement C5 preproprotein; Complement C5; complement C5; OTTHUMP00000022001; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; complement component 5; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4]
• Other_gene_names
  [C5; C5; CPAMD4; FLJ17816; FLJ17822; MGC142298; CPAMD4]
• Clonality
  Monoclonal
• Clone
  [5F207]
• Reactivity
  Human
• Specificity
  Recognizes human native C5 as well as with C5b. Allows detection of native complement component C5 and discrimination from activated C5b-9 complexes, especially in different forms of glomerulonephritis.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a lyophilized powder from PBS, pH7.4, 0.5% BSA, 0.09% sodium azide. Reconsitute with 1ml sterile ddH2O
• Concentration
  ~0.05mg/ml (after reconsitution)
• Storage_stability
  Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol, ddH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Complement  
• Gene symbol
  C5
• Short name
  Complement C5,
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans
• Alternative name
  Complement complement component 5, H. sapiens
• Alternative to gene target
  complement component 5, C5a and C5b and C5D and CPAMD4 and ECLZB, C5 and IDBG-83167 and ENSG00000106804 and 727, C5a anaphylatoxin chemotactic receptor binding, Extracellular, Hc and IDBG-163835 and ENSMUSG00000026874 and 15139, BT.24055 and IDBG-638834 and ENSBTAG00000012210 and 512045

Gene info

• Identity
  HGNC:1331
• Gene
  C5
• Long gene name
  complement C5
• Synonyms gene name
  • complement component 5
• Synonyms
  • CPAMD4
  • C5a
  • C5b
• Synonyms name
  • prepro-C5
  • C5a anaphylatoxin
• GenBank acession
  • M57729
• Locus
  9q33.2
• Discovery year
  2001-06-22
• Entrez gene record
  727
• RefSeq identity
  • NM_001735
• Classification
  • C3 and PZP like, alpha-2-macroglobulin domain containing
  • Complement system activation components
  • Receptor ligands
• VEGA ID
  OTTHUMG00000020579
• Locus Specific Databases
  • C5base: Mutation registry for C5 deficiency
  • LRG_28

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