Complement C5, Human Plasma

• Catalog number
  P1273-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  Compelement C5
• Alternative_names
  C5, CPAMD4
• Description
  A potent chemotactic factor for human peripheral blood neutrophils and monocytes
• Recombinant
  No
• Source
  Human Plasma
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  190 kDa
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Appearance
  Liquid
• Physical form description
  In PBS, pH 7.4
• Background Information
  Complement Component 5 (C5) plays a central role in inflammatory and cellular death processes. This protein is composed of alpha and beta polypeptide chains that are linked by a disulfide bridge. The protein gets cleaved into C5a and C5b which are subsequently responsible for chemotaxis, inflammation, and initiating the formation of the membrane attack complex (MAC). Drugs that inhibit complement C5 have been used in Paroxysmal nocturnal hemoglobinuria (PNH) patients to lessen thrombotic complications by lessening intravascular hemolysis.
• Handling
  Thaw on ice, and aliquot into smaller working quantities to avoid multiple freeze/thaw cycles.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Complement   Plasma  
• Short name
  Complement C5, Plasma
• Species
  Human, Humans
• Alternative name
  Complement complement component 5, H. sapiens Plasma
• Alternative to gene target
  complement component 5, C5a and C5b and C5D and CPAMD4 and ECLZB, C5 and IDBG-83167 and ENSG00000106804 and 727, C5a anaphylatoxin chemotactic receptor binding, Extracellular, Hc and IDBG-163835 and ENSMUSG00000026874 and 15139, BT.24055 and IDBG-638834 and ENSBTAG00000012210 and 512045

Product images

Similar products