Clostridium Neurotoxin Type C1 Heavy Chain (BoNT-C1) (Biotin)

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Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated

Gene target

Clostridium Neurotoxin Heavy Chain BoNT-C1
Gene symbol

SNAR-C1, TRGC1, PFDN4, TNS2, ARHGAP4, MAGEC1, SERPING1, PLAAT1
Short name

Clostridium Neurotoxin C1 Heavy Chain (BoNT-C1) ( )
Label

Biotin
Alternative name

Clostridium Neurotoxin classification C1 Heavy epitope (BoNT-C1) (biotinilated)

Identity

HGNC:19737
Gene

TNS2
Long gene name

tensin 2
Synonyms gene
- TENC1
Synonyms gene name
- tensin like C1 domain-containing phosphatase
- tensin like C1 domain containing phosphatase (tensin 2)
Synonyms
- KIAA1075
- C1-TEN
GenBank acession
- AF518729
Locus

12q13.13
Discovery year

2002-12-09
Entrez gene record

23371
RefSeq identity
- NM_170754
Classification
- PTEN protein phosphatases
- SH2 domain containing
- C2 tensin-type domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000169730

Identity

HGNC:674
Gene

ARHGAP4
Long gene name

Rho GTPase activating protein 4
Synonyms
- KIAA0131
- C1
- p115
- RhoGAP4
- SrGAP4
Synonyms name
- Rho-GAP hematopoietic protein C1
GenBank acession
- X78817
Locus

Xq28
Discovery year

1997-08-28
Entrez gene record

393
Pubmed identfication
- 8570618
RefSeq identity
- NM_001666
Classification
- AH/BAR family Rho GTPase activating proteins
- F-BAR domain containing
VEGA ID

OTTHUMG00000024226
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:1228
Gene

SERPING1
Long gene name

serpin family G member 1
Synonyms gene
- C1NH
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
- serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms
- C1IN
- C1-INH
- HAE1
- HAE2
- C1INH
Synonyms name
GenBank acession
- X54486
Locus

11q12.1
Discovery year

2001-06-22
Entrez gene record

710
Pubmed identfication
- 2026152
- 24172014
RefSeq identity
- NM_000062
Classification
- Complement system regulators and receptors
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000150304
Locus Specific Databases
- SERPING1base: Mutation registry for Hereditary angioedema
- LRG_105