Clostridium botulinum Neurotoxin Type C1 Heavy Chain (BoNT-C1)

Products_type

Antibody
Products_short_name

[Clostridium botulinum Neurotoxin Type C1 Heavy Chain]
Products_name_syn

[Anti -Clostridium botulinum Neurotoxin Type C1 Heavy Chain (BoNT-C1)]
Clonality

Polyclonal
Specificity

Recognizes BoNT-C1 Heavy Chain in ELISA and Western Blot. Crossreacts with rBoNT-D-HCR (10%) and rBoNT-A-HCR, rBoNT-A-LC, and rBoNT-B-LC (5%).
Purity

Affinity Purified Purified by immunoaffinity chromatography.
Form

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
Storage_stability

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)

Gene target

Clostridium botulinum Neurotoxin Heavy Chain BoNT-C1
Gene symbol

SNAR-C1, TRGC1, PFDN4, TNS2, ARHGAP4, MAGEC1, SERPING1, PLAAT1
Short name

Clostridium botulinum Neurotoxin C1 Heavy Chain (BoNT-C1)
Host

Sheep
Isotype

IgG
Alternative name

Clostridium botulinum Neurotoxin classification C1 Heavy epitope (BoNT-C1)

Identity

HGNC:19737
Gene

TNS2
Long gene name

tensin 2
Synonyms gene
- TENC1
Synonyms gene name
- tensin like C1 domain-containing phosphatase
- tensin like C1 domain containing phosphatase (tensin 2)
Synonyms
- KIAA1075
- C1-TEN
GenBank acession
- AF518729
Locus

12q13.13
Discovery year

2002-12-09
Entrez gene record

23371
RefSeq identity
- NM_170754
Classification
- PTEN protein phosphatases
- SH2 domain containing
- C2 tensin-type domain containing
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000169730

Identity

HGNC:674
Gene

ARHGAP4
Long gene name

Rho GTPase activating protein 4
Synonyms
- KIAA0131
- C1
- p115
- RhoGAP4
- SrGAP4
Synonyms name
- Rho-GAP hematopoietic protein C1
GenBank acession
- X78817
Locus

Xq28
Discovery year

1997-08-28
Entrez gene record

393
Pubmed identfication
- 8570618
RefSeq identity
- NM_001666
Classification
- AH/BAR family Rho GTPase activating proteins
- F-BAR domain containing
VEGA ID

OTTHUMG00000024226
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:1228
Gene

SERPING1
Long gene name

serpin family G member 1
Synonyms gene
- C1NH
Synonyms gene name
- serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
- serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms
- C1IN
- C1-INH
- HAE1
- HAE2
- C1INH
Synonyms name
GenBank acession
- X54486
Locus

11q12.1
Discovery year

2001-06-22
Entrez gene record

710
Pubmed identfication
- 2026152
- 24172014
RefSeq identity
- NM_000062
Classification
- Complement system regulators and receptors
- Serpin peptidase inhibitors
VEGA ID

OTTHUMG00000150304
Locus Specific Databases
- SERPING1base: Mutation registry for Hereditary angioedema
- LRG_105