CD8 Biotin

Products_type

Antibody
Products_short_name

[CD8]
Products_name_syn

[CD8 Biotin]
Other_names

[T-cell surface glycoprotein CD8 alpha chain isoform 1; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 alpha chain; T8 T-cell antigen; T cell co-receptor; OKT8 T-cell antigen; T-cell antigen Leu2; Leu2 T-lymphocyte antigen; CD8 antigen, alpha polypeptide (p32); T-lymphocyte differentiation antigen T8/Leu-2; CD8a molecule; T-lymphocyte differentiation antigen T8/Leu-2]
Products_gene_name

[CD8]
Other_gene_names

[CD8A; CD8A; CD8; MAL; p32; Leu2; MAL]
Clone

[17D8]
Reactivity

Human
Purity

Protein A/G Chromatography
Form

Provided as sterile filtered solution in phosphate buffered saline with 0.08% sodium azide and 0.2% carrier protein
Storage_stability

Product should be stored at 4-8 degree C. DO NOT FREEZE
Tested_application

Flow Cytometry (FC/FACS)
Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated
Description

Cytotoxic T cells cluster differentiators for flow cytometry. This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity.

Identity

HGNC:1706
Gene

CD8A
Long gene name

CD8a molecule
Synonyms gene
- CD8
Synonyms gene name
- CD8 antigen, alpha polypeptide (p32)
- T-cell surface glycoprotein CD8 alpha chain
Locus

2p11.2
Discovery year

1986-01-01
Entrez gene record

925
Pubmed identfication
- 1541829
RefSeq identity
- NM_001768
Classification
- V-set domain containing
- CD molecules
VEGA ID

OTTHUMG00000130265
Locus Specific Databases
- CD8Abase: Mutation registry for CD8 deficiency
- LRG_44