CD2 / Lymphocyte Function Antigen 2 (LFA-2) Mouse Monoclonal Antibody
#
-
Catalog numberMBS438756
-
Price:
-
Size0.02 mg (With BSA & Azide at 0.2mg/mL)
-
-
Products_typeAntibody
-
Products_short_name[CD2 / Lymphocyte Function Antigen 2 (LFA-2)]
-
Products_name_syn[Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11]
-
Other_names[T-cell surface antigen CD2 isoform 2; T-cell surface antigen CD2; T-cell surface antigen CD2; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]
-
Products_gene_name[CD2]
-
Other_gene_names[CD2; CD2; T11; SRBC; LFA-2; SRBC]
-
ClonalityMonoclonal
-
Clone[HuLy-m1]
-
ReactivityHuman, Cat
-
SpecificityCD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
-
Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
-
Storage_stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Tested_applicationFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
-
PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
DescriptionAntigens are peptides or recombinant or native dependent on the production method.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus
-
French translationanticorps
-
Gene target
-
Gene symbolCD2, ITGAL, ITGB2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
-
Short nameCD2 / Lymphocyte Antigen 2 (LFA-2) Mouse Monoclonal Antibody
-
TechniqueMouse monoclonal, Antibody, antigen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
-
HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
-
IsotypeIgG2b, kappa
-
SpeciesMouse, Mouses
-
Alternative nameCD2 molecule / Lymphocyte Function protein 2 (LFA-2) Mouse monoclonal (antibody to-)
-
Alternative techniqueantibodies, antigenes, murine
-
Alternative to gene targetCD2 molecule, LFA-2 and SRBC and T11, CD2 and IDBG-101417 and ENSG00000116824 and 914, protein homodimerization activity, Extracellular, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022
-
Tissuelymphocyte
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD2 molecule
-
Synonyms gene
-
Synonyms gene name
- CD2 antigen (p50), sheep red blood cell receptor
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Ig-like cell adhesion molecule family
- C2-set domain containing
- V-set domain containing
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameintegrin subunit alpha L
-
Synonyms gene
-
Synonyms gene name
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Integrin alpha subunits
- CD molecules
- MicroRNA protein coding host genes
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nameintegrin subunit beta 2
-
Synonyms gene
-
Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1986-01-01
-
Entrez gene record
-
RefSeq identity
-
Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 7-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR7 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 329-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-11
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR329 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 512-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 521-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR515 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1289-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1289 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 509-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR506 family
Gene info
-
Identity
-
Gene
-
Long gene namekeratin associated protein 13-2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-02-21
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Keratin associated proteins
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data