- Catalog numberMBS439760
- Product nameCD2 / Lymphocyte Function Antigen 2 (LFA-2) Mouse Monoclonal Antibody
- Size0.1 mg (With BSA & Azide at 0.2mg/mL)
- PriceAsk For Price
- Products typeAntibody
- Products short name[CD2 / Lymphocyte Function Antigen 2 (LFA-2)]
- Products name syn[Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11]
- Other names[T-cell surface antigen CD2 isoform 2; T-cell surface antigen CD2; T-cell surface antigen CD2; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]
- Products gene name[CD2]
- Other gene names[CD2; CD2; T11; SRBC; LFA-2; SRBC]
- ClonalityMonoclonal
- IsotypeIgG1, kappa
- Clone[LFA2/600]
- HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
- ReactivityHuman, Non-human Primates, Pig
- SpecificityCD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
- Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Storage stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Tested applicationFlow Cytometry (FC/FACS), Immunofluorescence (IF)
- Alternative to gene target
- [ "CD2 molecule", "LFA-2 and SRBC and T11", "CD2 and IDBG-101417 and ENSG00000116824 and 914", "protein homodimerization activity", "Extracellular", "Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481", "CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022" ]
- Gene targetCD2 / Lymphocyte 2 LFA-2 Monoclonal
- Identity:HGNC:1639
- Gene:CD2
- Long gene name:CD2 molecule
- Synonyms gene name:CD2 antigen (p50), sheep red blood cell receptor
- Discovery year:1986-01-01
- Entrez gene record:914
- Pubmed identification:2437578
- RefSeq identity:NM_001767
- Classification:CD molecules, Ig-like cell adhesion molecule family, C2-set domain containing, V-set domain containing
- VEGA ID:OTTHUMG00000022750
- Identity:HGNC:6148
- Gene:ITGAL
- Long gene name:integrin subunit alpha L
- Synonyms gene name:integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
- Synonyms:LFA-1LFA1A
- Discovery year:1986-01-01
- Entrez gene record:3683
- Pubmed identification:3284962
- Classification:Integrin alpha subunits, CD molecules, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000176964
- Identity:HGNC:6155
- Gene:ITGB2
- Long gene name:integrin subunit beta 2
- Synonyms gene name:integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
- Synonyms:LFA-1, MAC-1
- Discovery year:1986-01-01
- Entrez gene record:3689
- RefSeq identity:NM_000211
- Classification:Integrin beta subunits, Complement system regulators and receptors, CD molecules
- VEGA ID:OTTHUMG00000090257
- Identity:HGNC:31639
- Gene:MIR7-2
- Long gene name:microRNA 7-2
- Synonyms:hsa-mir-7-2
- Discovery year:2004-04-23
- Entrez gene record:407044
- RefSeq identity:NR_029606
- Classification:MicroRNA MIR7 family
- Identity:HGNC:32051
- Gene:MIR329-2
- Long gene name:microRNA 329-2
- Synonyms:hsa-mir-329-2
- Discovery year:2005-07-11
- Entrez gene record:574409
- RefSeq identity:NR_029968
- Classification:MicroRNA MIR329 family
- Identity:HGNC:32091
- Gene:MIR512-2
- Long gene name:microRNA 512-2
- Synonyms:hsa-mir-512-2
- Discovery year:2005-07-15
- Entrez gene record:574459
- RefSeq identity:NR_030181
- Classification:MicroRNA MIR506 family
- Identity:HGNC:32113
- Gene:MIR521-2
- Long gene name:microRNA 521-2
- Synonyms:hsa-mir-521-2
- Discovery year:2005-07-15
- Entrez gene record:574481
- RefSeq identity:NR_030203
- Classification:MicroRNA MIR515 family
- Identity:HGNC:35282
- Gene:MIR1289-2
- Long gene name:microRNA 1289-2
- Synonyms:hsa-mir-1289-2
- Discovery year:2008-11-03
- Entrez gene record:100302134
- RefSeq identity:NR_031621
- Classification:MicroRNA MIR1289 family
- Identity:HGNC:33641
- Gene:MIR509-2
- Long gene name:microRNA 509-2
- Synonyms:hsa-mir-509-2
- Discovery year:2007-10-24
- Entrez gene record:100126301
- RefSeq identity:NR_030586
- Classification:MicroRNA MIR506 family
- Identity:HGNC:18923
- Gene:KRTAP13-2
- Long gene name:keratin associated protein 13-2
- Synonyms:KAP13-2
- Discovery year:2003-02-21
- Entrez gene record:337959
- Pubmed identification:12359730
- Classification:Keratin associated proteins
- VEGA ID:OTTHUMG00000057793
- Gene symbolCD2, ITGAL, ITGB2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2
- isotype filter
- IgG1
- kappa
- Short nameCD2 / Lymphocyte Antigen 2 (LFA-2) Mouse Monoclonal Antibody
- technique filter
- Mouse monoclonal
- Antibody
- antigen
- Mouse
- TechniqueMouse monoclonal, Antibody, antigen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
- Alternative techniqueantibodies, antigenes, murine
- Tissuelymphocyte
- tissue filter
- lymphocyte
Gene info
Gene info
Gene info
Locus Specific Databases:ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)LRG_76