CD1b

• Catalog number
  MBS438097
• Price
  Please ask
• Size
  0.1 mg (Without BSA & Azide at 1mg/mL)

• Products_type
  Antibody
• Products_short_name
  [CD1b]
• Products_name_syn
  [A1 domain; CD1A; Cortical thymocyte antigen CD1A; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1a; T6/Leu6]
• Other_names
  [T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; CD1b molecule; CD_antigen: CD1b]
• Products_gene_name
  [CD1B]
• Other_gene_names
  [CD1B; CD1B; R1; CD1; CD1A]
• Clonality
  Monoclonal
• Clone
  [RIV12]
• Reactivity
  Human.
• Specificity
  The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Store at 2 to 8 degree C. Antibody is stable for 24 months.
• Tested_application
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  CD1b  
• Gene symbol
  CD1B
• Short name
  CD1b
• Host
  Mouse
• Isotype
  IgG1, kappa
• Alternative name
  CD1b molecule
• Alternative to gene target
  CD1b molecule, CD1 and CD1A and R1, CD1B and IDBG-103744 and ENSG00000158485 and 910, protein binding, Plasma membranes

Gene info

• Identity
  HGNC:1635
• Gene
  CD1B
• Long gene name
  CD1b molecule
• Synonyms gene
  • CD1
• Synonyms gene name
  • CD1B antigen, b polypeptide
  • CD1b antigen
• GenBank acession
  • M28826
• Locus
  1q23.1
• Discovery year
  1988-05-11
• Entrez gene record
  910
• Pubmed identfication
  • 2447586
• RefSeq identity
  • NM_001764
• Classification
  • CD molecules
  • C1-set domain containing
• VEGA ID
  OTTHUMG00000017513

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