CD1b
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Catalog numberMBS438097
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PricePlease ask
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Size0.02 mg (With BSA & Azide at 0.2mg/mL)
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Products_typeAntibody
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Products_short_name[CD1b]
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Products_name_syn[A1 domain; CD1A; Cortical thymocyte antigen CD1A; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1a; T6/Leu6]
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Other_names[T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; T-cell surface glycoprotein CD1b; CD1B antigen, b polypeptide; cortical thymocyte antigen CD1B; differentiation antigen CD1-alpha-3; CD1b molecule; CD_antigen: CD1b]
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Products_gene_name[CD1B]
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Other_gene_names[CD1B; CD1B; R1; CD1; CD1A]
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ClonalityMonoclonal
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Clone[RIV12]
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ReactivityHuman.
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SpecificityThe mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
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Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stabilityStore at 2 to 8 degree C. Antibody is stable for 24 months.
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Tested_applicationELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)
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Gene target
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Gene symbolCD1B
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Short nameCD1b
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HostMouse
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IsotypeIgG1, kappa
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Alternative nameCD1b molecule
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Alternative to gene targetCD1b molecule, CD1 and CD1A and R1, CD1B and IDBG-103744 and ENSG00000158485 and 910, protein binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene nameCD1b molecule
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Synonyms gene
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Synonyms gene name
- CD1B antigen, b polypeptide
- CD1b antigen
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GenBank acession
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- C1-set domain containing
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VEGA ID