CD134 Ligand (CD134L, OX40L, CD252) (Biotin)

Products_type

Antibody
Products_short_name

[CD134 Ligand]
Products_name_syn

[Anti -CD134 Ligand (CD134L, OX40L, CD252) (Biotin)]
Other_names

[CD134(OX40)-ligand; tumor necrosis factor ligand superfamily member 4; CD134(OX40)-ligand]
Other_gene_names

[TNFSF4]
Clonality

Monoclonal
Clone

[7H146]
Reactivity

Human
Specificity

Recognizes human CD134 ligand.
Purity

Affinity Purified Purified by Protein A affinity chromatography.
Form

Supplied as a liquid in PBS, 100mM potasssium chloride, pH 7.5, 0.2% BSA, 0.04% sodium azide, 5% glycerol. Labeled with Biotin.
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Properties

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Conjugation

Biotinylated
Description

FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Identity

HGNC:11934
Gene

TNFSF4
Long gene name

TNF superfamily member 4
Synonyms gene
- TXGP1
Synonyms gene name
- tax-transcriptionally activated glycoprotein 1, 34kD
- tumor necrosis factor (ligand) superfamily, member 4
Synonyms
- OX-40L
- gp34
- CD252
GenBank acession
- D90224
Locus

1q25.1
Discovery year

1993-12-15
Entrez gene record

7292
Pubmed identfication
- 1996093
- 8076595
Classification
- Tumor necrosis factor superfamily
- CD molecules
VEGA ID

OTTHUMG00000034838