Caspase 1, beta (Interleukin-1 Beta Converting Enzyme, ICE) Substrate IV [Ac-Tyr-Val-Ala-Asp-pNA]
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Catalog numberMBS657955
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Price:
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Size1 mg
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Products_typePeptide
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Products_short_name[Caspase 1, beta]
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Other_names[caspase-1; Caspase-1; caspase-1; p45; CASP-1; IL-1BC; IL-1 beta-converting enzyme; interleukin-1 beta convertase; interleukin 1, beta, convertase; Interleukin 1beta converting enzyme; interleukin-1 beta-converting enzyme; caspase 1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45]
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Other_gene_names[Casp1; Casp1; Ice; Il1bc; Il1bc; Il1bce; CASP-1; IL-1BC; ICE]
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PurityHighly Purified~95%. Purified by HPLC.
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FormSupplied as a lyophilized powder.
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Storage_stabilityLyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer._x000B_ _x000B_
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DescriptionHuman and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbolCASP1, CASP5, CES2, CARD18, CARD16, CASP4, CASP9, CASP7
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Short nameCaspase 1, beta (Interleukin-1 Beta Converting Enzyme, ICE) Substrate IV [Ac-Tyr-Val-Ala-Asp-pNA]
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TechniqueEnzyme, enzymes
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HostSynthetic peptide
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Alternative namecaspase 1, b (Interleukin-1 b Converting Enzyme, ICE) Substrate IV [Ac-L-tyrosine-L-valine-alanine-L-aspartic acid-pNA]
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Alternative techniqueenzymes
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Gene info
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Identity
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Gene
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Long gene namecaspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carboxylesterases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 18
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Synonyms gene name
- caspase recruitment domain family, member 18
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-09-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase recruitment domain family member 16
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Synonyms gene name
- caspase recruitment domain family, member 16
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Synonyms
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Locus
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Discovery year2008-09-15
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Entrez gene record
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Pubmed identfication
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Classification
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 4
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Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecaspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
- E05.599.495