Caspase 1, beta (Interleukin-1 Beta Converting Enzyme, ICE) Substrate IV [Ac-Tyr-Val-Ala-Asp-pNA]
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Catalog number
MBS657955
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Price
Please ask
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Size
5x1 mg
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Products_type
Peptide
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Products_short_name
[Caspase 1, beta]
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Other_names
[caspase-1; Caspase-1; caspase-1; p45; CASP-1; IL-1BC; IL-1 beta-converting enzyme; interleukin-1 beta convertase; interleukin 1, beta, convertase; Interleukin 1beta converting enzyme; interleukin-1 beta-converting enzyme; caspase 1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45]
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Other_gene_names
[Casp1; Casp1; Ice; Il1bc; Il1bc; Il1bce; CASP-1; IL-1BC; ICE]
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Purity
Highly Purified~95%. Purified by HPLC.
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Form
Supplied as a lyophilized powder.
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Storage_stability
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer._x000B_ _x000B_
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Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbol
CASP1, CASP5, CES2, CARD18, CARD16, CASP4, CASP9, CASP7
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Short name
Caspase 1, beta (Interleukin-1 Beta Converting Enzyme, ICE) Substrate IV [Ac-Tyr-Val-Ala-Asp-pNA]
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Technique
Enzyme, enzymes
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Host
Synthetic peptide
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Alternative name
caspase 1, b (Interleukin-1 b Converting Enzyme, ICE) Substrate IV [Ac-L-tyrosine-L-valine-alanine-L-aspartic acid-pNA]
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Alternative technique
enzymes
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Gene info
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Identity
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Gene
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Long gene name
caspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year
1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
carboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
caspase 4
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Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
Product images
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