CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)
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Catalog number
MBS648344
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Price
Please ask
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Size
0.1 mg
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Products_type
Antibody
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Products_short_name
[CASP10]
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Products_name_syn
[Anti -CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)]
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Other_names
[caspase-10 isoform 5 preproprotein; Caspase-10; caspase-10; CASP-10; FADD-like ICE2; apoptotic protease MCH-4; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine protease; FAS-associated death domain protein interleukin-1B-converting enzyme 2; caspase 10, apoptosis-related cysteine peptidase; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4]
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Other_gene_names
[CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2]
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Clonality
Monoclonal
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Reactivity
Human, Mouse
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Specificity
Recognizes human Caspase-10. Species Crossreactivity: mouse.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
Western Blot (WB)
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Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
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Gene target
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Gene symbol
CASP10, FAS-AS1, CASP1, FASN, IGHD1OR15-1B, XCL2, CASP5, CES2, CARD18, CASP9
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Short name
CASP10, CT (Caspase-10, CASP-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, FAS-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, Caspase-10 Subunit p23/17, Caspase-10 Subunit p12, MCH4)
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Technique
Enzyme, enzymes
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Host
Rat
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Isotype
IgG2a
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Alternative name
caspase 10, apoptosis-related cysteine peptidase, CT (caspase-10, caspase-10, ICE-like Apoptotic Protease 4, Apoptotic Protease Mch-4, Fas (tumor necrosis factor receptor superfamily, member 6)-associated Death Domain Protein Interleukin-1B-converting Enzyme 2, FLICE2, caspase-10 functionnal sequence p23/17, caspase-10 functionnal sequence p12, MCH4)
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Alternative technique
enzymes
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Alternative to gene target
caspase 10, apoptosis-related cysteine peptidase, ALPS2 and FLICE2 and MCH4, CASP10 and IDBG-78470 and ENSG00000003400 and 843, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene name
caspase 10
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Synonyms gene name
- caspase 10, apoptosis-related cysteine protease
- caspase 10, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-04-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
FAS antisense RNA 1
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Synonyms gene
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Synonyms gene name
- FAS antisense RNA (non-protein coding)
- FAS antisense RNA 1 (non-protein coding)
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Synonyms
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Locus
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Discovery year
2009-07-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
Gene info
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Identity
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Gene
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Long gene name
caspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
fatty acid synthase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1994-05-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Short chain dehydrogenase/reductase superfamily
- 7BS orphan methyltransferases
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
caspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year
1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
carboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
caspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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