CASP8, CT (Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, Caspase-8
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Catalog number
MBS644805
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Price
Please ask
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Size
5x0.2 mL
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Products_type
Antibody
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Products_short_name
[CASP8]
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Products_name_syn
[Anti -CASP8, CT (Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, Caspase-8]
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Other_names
[caspase-8 isoform G; caspase-8; caspase 8, apoptosis-related cysteine peptidase]
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Other_gene_names
[CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Recognizes human CASP8.
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Purity
Purified Purified by ammonium sulfate precipitation.
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Form
Supplied as a liquid in PBS, 0.09% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
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Gene
Cys or cysteines ChEMBL54943
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Gene target
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Gene symbol
FADD, CASP8, CASP1, CASP9, CASP5, CES2, CARD18, CARD16, CASP4, CASP7
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Short name
CASP8, CT (Caspase-8, CASP-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, FADD-homologous ICE/CED-3-like Protease, FADD-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, Caspase-8 Subunit p18, Caspase-8
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Host
Rabbit
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Isotype
IgG
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Alternative name
caspase 8, apoptosis-related cysteine peptidase, CT (caspase-8, caspase-8, ICE-like Apoptotic Protease 5, MORT1-associated CED-3 Homolog, MACH, Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-homologous ICE/CED-3-like Protease, Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain-like ICE, FLICE, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, caspase-8 functionnal sequence p18, caspase-8
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Alternative to gene target
Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720
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Gene info
Gene info
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Identity
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Gene
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Long gene name
caspase 8
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Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene name
caspase 1
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Synonyms gene
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Synonyms gene name
- caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
- caspase 1, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-05-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 9
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Synonyms gene name
- caspase 9, apoptosis-related cysteine protease
- caspase 9, apoptosis-related cysteine peptidase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1996-11-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Apoptosome
- Caspase recruitment domain containing
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 5
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Synonyms gene name
- caspase 5, apoptosis-related cysteine protease
- caspase 5, apoptosis-related cysteine peptidase
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Synonyms
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Locus
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Discovery year
1996-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
carboxylesterase 2
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Synonyms gene name
- carboxylesterase 2 (intestine, liver)
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Synonyms
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GenBank acession
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Locus
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Discovery year
1993-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
caspase 4
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Synonyms gene name
- caspase 4, apoptosis-related cysteine protease
- caspase 4, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Caspases
- Caspase recruitment domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
caspase 7
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Synonyms gene name
- caspase 7, apoptosis-related cysteine protease
- caspase 7, apoptosis-related cysteine peptidase
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
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Tree numbers
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