BRCA1 Monoclonal Antibody

• Catalog number
  MBS190076
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [BRCA1]
• Products_name_syn
  [Anti-BRCA1; BRCA1]
• Other_names
  [BRCA1; Breast cancer type 1 susceptibility protein; breast cancer type 1 susceptibility protein; OTTHUMP00000212143; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; RING finger protein 53; BRCA1/BRCA2-containing complex, subunit 1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein; breast cancer 1, early onset; RING finger protein 53]
• Other_gene_names
  [BRCA1; BRCA1; IRIS; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; RNF53]
• Clonality
  Monoclonal
• Specificity
  Anti-BRCA1 [Murine MAb recognizes full-length BRCA1 and does not recognize the Dexon 11 splice variant.] This antibody recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the delta exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
• Form
  100 ug Protein G purified antibody in PBS, pH 7.4
• Storage_stability
  This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
• Tested_application
  Immunoblot, Immunohistochemistry, Immunoprecipitation
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  BRCA1   Monoclonal  
• Gene symbol
  BRCA1, BRCA1P1
• Short name
  BRCA1 Monoclonal Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse
• Isotype
  IgG1 kappa
• Alternative name
  breast cancer 1, early onset monoclonal (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  breast cancer 1, early onset, BRCAI and BRCC1 and BROVCA1 and IRIS and PNCA4 and PPP1R53 and PSCP and RNF53, BRCA1 and IDBG-52172 and ENSG00000012048 and 672, androgen receptor binding, nuclei, Brca1 and IDBG-212218 and ENSMUSG00000017146 and 12189, BRCA1 and IDBG-640630 and ENSBTAG00000022520 and 353120

Gene info

• Identity
  HGNC:1100
• Gene
  BRCA1
• Long gene name
  BRCA1 DNA repair associated
• Synonyms gene name
  • breast cancer 1, early onset
  • breast cancer 1
• Synonyms
  • RNF53
  • BRCC1
  • PPP1R53
  • FANCS
• Synonyms name
  • BRCA1/BRCA2-containing complex, subunit 1
  • protein phosphatase 1, regulatory subunit 53
  • Fanconi anemia, complementation group S
• GenBank acession
  • U14680
• Locus
  17q21.31
• Discovery year
  1991-02-20
• Entrez gene record
  672
• Pubmed identfication
  • 1676470
  • 25472942
• RefSeq identity
  • NM_007294
• Classification
  • Ring finger proteins
  • Protein phosphatase 1 regulatory subunits
  • BRCA1 A complex
  • BRCA1 B complex
  • BRCA1 C complex
  • FA complementation groups
• VEGA ID
  OTTHUMG00000157426
• Locus Specific Databases
  • Breast Cancer
  • Fanconi Anaemia Mutation Database
  • BRCA1 database at LOVD-China
  • Global Variome shared LOVD
  • LOVD - Leiden Open Variation Database
  • LRG_292

Gene info

• Identity
  HGNC:28470
• Gene
  BRCA1P1
• Long gene name
  BRCA1 pseudogene 1
• Synonyms
  • LBRCA1
  • PsiBRCA1
  • pseudo-BRCA1
• Synonyms name
  • like-BRCA1
• Locus
  17q21.31
• Discovery year
  2005-05-26
• Entrez gene record
  394269
• Pubmed identfication
  • 11880951
  • 8954804
  • 10205276
• RefSeq identity
  • NG_003183

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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