Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor Type IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)
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Catalog numberMBS616055
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Price:
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Size5x0.1 mg
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Products_typeAntibody
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Products_short_name[Bone Morphogenic Protein Receptor 1A]
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Products_name_syn[Anti -Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor Type IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)]
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Other_names[bone morphogenetic protein receptor type-1A; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor type-1A; ALK-3; BMPR-1A; OTTHUMP00000020014; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; bone morphogenetic protein receptor, type IA; Activin receptor-like kinase 3; ALK-3; Serine/threonine-protein kinase receptor R5]
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Other_gene_names[BMPR1A; BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del; ACVRLK3; ALK3]
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ClonalityPolyclonal
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ReactivityHuman
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SpecificityRecognizes human BMPR-1A at ~60 kD. Reactivity has been confirmed with human SK-OV-3, NGP96, SKMEL-19, SK-MEL-37, A375, MeWo cell lysates and mouse ovary homogenates. Based on amino acid sequence homology, reactivity with rat is also expected. Species sequence homology: rat.
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PurityAffinity Purified Purified by immunoaffinity chromatography
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FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
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Gene target
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Gene symbolBMPR1A, BMPR2, HIF1A-AS2, IGHD1OR15-1A, ALK, ENPP7, UBP1, MTNR1A, IGKV2OR2-1, SCLT1
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Short nameBone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)
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HostRabbit
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IsotypeIgG
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Alternative nameBone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor classification IA, Serine Threonine Protein phosphorylation catalyst Receptor R5, SKR5, Activin Receptor-like phosphorylation catalyst 3, anaplastic lymphoma receptor tyrosine kinase-3, ACVRLK3)
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Alternative to gene targetanaplastic lymphoma receptor tyrosine kinase, CD246 and NBLST3, ALK and IDBG-42084 and ENSG00000171094 and 238, transferase activity, Plasma membranes, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642
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Tissuebone
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Gene info
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Identity
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Gene
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Long gene namebone morphogenetic protein receptor type 1A
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Synonyms gene
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Synonyms gene name
- bone morphogenetic protein receptor, type IA
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-12-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Type 1 receptor serine/threonine kinases
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namebone morphogenetic protein receptor type 2
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Synonyms gene
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Synonyms gene name
- primary pulmonary hypertension 1
- bone morphogenetic protein receptor, type II (serine/threonine kinase)
- bone morphogenetic protein receptor type II
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-03-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Type 2 receptor serine/threonine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameHIF1A antisense RNA 2
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Synonyms gene name
- HIF1A antisense RNA 2 (non-protein coding)
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Synonyms
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Locus
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Discovery year2011-09-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy diversity 1/OR15-1A (non-functional)
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Synonyms gene name
- immunoglobulin heavy diversity 1/OR15-1A
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameALK receptor tyrosine kinase
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Synonyms gene name
- anaplastic lymphoma kinase (Ki-1)
- anaplastic lymphoma receptor tyrosine kinase
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor tyrosine kinases
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameectonucleotide pyrophosphatase/phosphodiesterase 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-04-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ectonucleotide pyrophosphatase/phosphodiesterase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameupstream binding protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemelatonin receptor 1A
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Synonyms
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Locus
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Discovery year1995-03-22
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Entrez gene record
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Pubmed identfication
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Classification
- Melatonin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 2/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 2/OR2-1
- immunoglobulin kappa variable 2/OR2-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesodium channel and clathrin linker 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-07-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID