Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor Type IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)

• Catalog number
  MBS616055
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Bone Morphogenic Protein Receptor 1A]
• Products_name_syn
  [Anti -Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor Type IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)]
• Other_names
  [bone morphogenetic protein receptor type-1A; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor type-1A; ALK-3; BMPR-1A; OTTHUMP00000020014; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; bone morphogenetic protein receptor, type IA; Activin receptor-like kinase 3; ALK-3; Serine/threonine-protein kinase receptor R5]
• Other_gene_names
  [BMPR1A; BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del; ACVRLK3; ALK3]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human BMPR-1A at ~60 kD. Reactivity has been confirmed with human SK-OV-3, NGP96, SKMEL-19, SK-MEL-37, A375, MeWo cell lysates and mouse ovary homogenates. Based on amino acid sequence homology, reactivity with rat is also expected. Species sequence homology: rat.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  Bone   Morphogenic   Protein   Receptor   CD292   BMPR-1A   Bone   Morphogenetic   Protein   Receptor   Serine   Threonine   Protein   Kinase   Receptor   SKR5   Activin   Receptor-like   Kinase   ALK-3   ACVRLK3  
• Gene symbol
  BMPR1A, BMPR2, HIF1A-AS2, IGHD1OR15-1A, ALK, ENPP7, UBP1, MTNR1A, IGKV2OR2-1, SCLT1
• Short name
  Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor IA, Serine Threonine Protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, ACVRLK3)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Bone Morphogenic Protein Receptor 1A (CD292, BMPR-1A, Bone Morphogenetic Protein Receptor classification IA, Serine Threonine Protein phosphorylation catalyst Receptor R5, SKR5, Activin Receptor-like phosphorylation catalyst 3, anaplastic lymphoma receptor tyrosine kinase-3, ACVRLK3)
• Alternative to gene target
  anaplastic lymphoma receptor tyrosine kinase, CD246 and NBLST3, ALK and IDBG-42084 and ENSG00000171094 and 238, transferase activity, Plasma membranes, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642
• Tissue
  bone

Gene info

• Identity
  HGNC:1076
• Gene
  BMPR1A
• Long gene name
  bone morphogenetic protein receptor type 1A
• Synonyms gene
  • ACVRLK3
• Synonyms gene name
  • bone morphogenetic protein receptor, type IA
• Synonyms
  • ALK3
  • CD292
• GenBank acession
  • BC028383
• Locus
  10q23.2
• Discovery year
  1994-12-12
• Entrez gene record
  657
• Pubmed identfication
  • 8397373
  • 9730621
• RefSeq identity
  • NM_004329
• Classification
  • Type 1 receptor serine/threonine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000018657
• Locus Specific Databases
  • LRG_298

Gene info

• Identity
  HGNC:1078
• Gene
  BMPR2
• Long gene name
  bone morphogenetic protein receptor type 2
• Synonyms gene
  • PPH1
• Synonyms gene name
  • primary pulmonary hypertension 1
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • bone morphogenetic protein receptor type II
• Synonyms
  • BRK-3
  • T-ALK
  • BMPR3
  • BMPR-II
• GenBank acession
  • Z48923
• Locus
  2q33.1-q33.2
• Discovery year
  1997-03-19
• Entrez gene record
  659
• Pubmed identfication
  • 7791754
• RefSeq identity
  • NM_001204
• Classification
  • Type 2 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000133617
• Locus Specific Databases
  • LRG_712

Gene info

• Identity
  HGNC:43015
• Gene
  HIF1A-AS2
• Long gene name
  HIF1A antisense RNA 2
• Synonyms gene name
  • HIF1A antisense RNA 2 (non-protein coding)
• Synonyms
  • 3'aHIF-1A
  • aHIF
• Locus
  14q23.2
• Discovery year
  2011-09-16
• Entrez gene record
  100750247
• Pubmed identfication
  • 21897117
  • 27018306
• RefSeq identity
  • NR_045406
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000171135

Gene info

• Identity
  HGNC:5487
• Gene
  IGHD1OR15-1A
• Long gene name
  immunoglobulin heavy diversity 1/OR15-1A (non-functional)
• Synonyms gene name
  • immunoglobulin heavy diversity 1/OR15-1A
• Synonyms
  • IGHD1/OR15-1A
  • IGHD1OR151A
• GenBank acession
  • X55575
• Locus
  15q11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28335
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000184580

Gene info

• Identity
  HGNC:427
• Gene
  ALK
• Long gene name
  ALK receptor tyrosine kinase
• Synonyms gene name
  • anaplastic lymphoma kinase (Ki-1)
  • anaplastic lymphoma receptor tyrosine kinase
• Synonyms
  • CD246
  • ALK1
• GenBank acession
  • D45915
• Locus
  2p23.2-p23.1
• Discovery year
  1993-08-24
• Entrez gene record
  238
• Pubmed identfication
  • 8122112
• RefSeq identity
  • NM_004304
• Classification
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000152034
• Locus Specific Databases
  • LRG_488

Gene info

• Identity
  HGNC:23764
• Gene
  ENPP7
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 7
• Synonyms
  • alk-SMase
  • NPP7
• Synonyms name
  • alkaline sphingomyelinase
• GenBank acession
  • AY230663
• Locus
  17q25.3
• Discovery year
  2004-04-29
• Entrez gene record
  339221
• Pubmed identfication
  • 12885774
• RefSeq identity
  • NM_178543
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000177462

Gene info

• Identity
  HGNC:12507
• Gene
  UBP1
• Long gene name
  upstream binding protein 1
• Synonyms
  • LBP-1a
• GenBank acession
  • AF198487
• Locus
  3p22.3
• Discovery year
  1996-05-13
• Entrez gene record
  7342
• Pubmed identfication
  • 8114710
• RefSeq identity
  • NM_014517
• VEGA ID
  OTTHUMG00000130749

Gene info

• Identity
  HGNC:7463
• Gene
  MTNR1A
• Long gene name
  melatonin receptor 1A
• Synonyms
  • MEL-1A-R
• Locus
  4q35.2
• Discovery year
  1995-03-22
• Entrez gene record
  4543
• Pubmed identfication
  • 7558006
• Classification
  • Melatonin receptors
• VEGA ID
  OTTHUMG00000185575

Gene info

• Identity
  HGNC:5805
• Gene
  IGKV2OR2-1
• Long gene name
  immunoglobulin kappa variable 2/OR2-1 (pseudogene)
• Synonyms gene
  • IGKV2OR2-1A
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-1
  • immunoglobulin kappa variable 2/OR2-1 pseudogene
• Synonyms
  • IGKV2/OR2-1
  • IGKV2/OR2-1A
• GenBank acession
  • X05101
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28861
• Pubmed identfication
  • 8011175
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155332

Gene info

• Identity
  HGNC:26406
• Gene
  SCLT1
• Long gene name
  sodium channel and clathrin linker 1
• Synonyms
  • hCAP-1A
  • FLJ30655
• GenBank acession
  • AK055217
• Locus
  4q28.2
• Discovery year
  2006-07-18
• Entrez gene record
  132320
• Pubmed identfication
  • 15797711
• RefSeq identity
  • NM_144643
• VEGA ID
  OTTHUMG00000133346

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