Anti-Thyroid Hormone Receptor, alpha1/alpha2-Isotype

• Catalog number
  MBS500020
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Thyroid Hormone Receptor, a1/a2-Isotype]
• Other_names
  [thyroid hormone receptor alpha isoform 3; Thyroid hormone receptor alpha; thyroid hormone receptor alpha; EAR-7; c-erbA-alpha; ERBA-related 7; V-erbA-related protein 7; triiodothyronine receptor; nuclear receptor subfamily 1 group A member 1; thyroid normone nuclear receptor alpha variant 1; thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian); thyroid hormone receptor, alpha; Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha]
• Products_gene_name
  [THRA]
• Other_gene_names
  [THRA; THRA; AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; ERB-T-1; c-ERBA-1; EAR7; ERBA1; NR1A1; THRA1; THRA2; EAR-7]
• Clonality
  Monoclonal
• Clone
  [1718]
• Reactivity
  Human, rat
• Specificity
  Specific for the ~50k TR-alpha1 and the ~58k TR-alpha2 protein.
• Purity
  Protein G purified (Prepared from mouse ascites by ammonium sulfate precipitation followed by affinity purification on a protein G column.)
• Form
  100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
• Storage_stability
  Store at -20 degree C; stable for at least 1 year.
• Tested_application
  Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Immunoglobulin Isotype specific antibodies and controls are specific to the immunoglobulin heavy chains and immunoglobulin light chains. Mouse monoclonal antibodies from this clone have all the same affinity to the antigen. Also polyclonal antibodies are Isotype purified amd conjugated or if they are used as control non conjugated.
• Group
  isotypes

• Gene target
  Thyroid   Hormone   Receptor   alpha1/alpha2  
• Short name
  Anti-Thyroid Hormone Receptor, alpha1/alpha2-Isotype
• Technique
  Isotype, anti-, anti, antibody to, antibodies, Isotypes and controls
• Host
  Mouse
• Isotype
  IgG2A
• Alternative name
  Antibody toThyroid Hormone Receptor, alpha1/alpha2-isoform
• Alternative technique
  control, antibodies
• Tissue
  thyroid

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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