Leptin Receptor (OBR, LEPR, B219, Obese Receptor)

• Catalog number
  MBS606437
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Leptin Receptor]
• Products_name_syn
  [Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor)]
• Other_names
  [leptin receptor; Leptin receptor; leptin receptor; huB219; OB receptor; OTTHUMP00000010692; OTTHUMP00000010693; OTTHUMP00000010694; OTTHUMP00000010695; leptin receptor; HuB219; OB receptor]
• Other_gene_names
  [LEPR; LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731; DB; OBR]
• Clonality
  Monoclonal
• Clone
  [5i316]
• Reactivity
  Human
• Specificity
  Recognizes human Leptin Receptor. Does not react with mouse.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a lyophillized powder from 0.05M PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
• Storage_stability
  Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Gene
  Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Leptin   Receptor   OBR   LEPR   B219   Obese   Receptor  
• Gene symbol
  LEPR
• Short name
  Leptin Receptor (OBR, LEPR, B219, Obese Receptor)
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Leptin Receptor (OBR, leptin receptor, B219, Obese Receptor)
• Alternative to gene target
  leptin receptor, CD295 and LEP-R and LEPRD and OB-R and OBR, LEPR and IDBG-99469 and ENSG00000116678 and 3953, identical protein binding, Extracellular, Lepr and IDBG-167734 and ENSMUSG00000057722 and 16847, LEPR and IDBG-638266 and ENSBTAG00000005910 and 497205,785813

Gene info

• Identity
  HGNC:6554
• Gene
  LEPR
• Long gene name
  leptin receptor
• Synonyms
  • OBR
  • CD295
• GenBank acession
  • U43168
• Locus
  1p31.3
• Discovery year
  1996-05-09
• Entrez gene record
  3953
• Pubmed identfication
  • 8548812
  • 8812446
• RefSeq identity
  • NM_002303
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000009115
• Locus Specific Databases
  • LRG_283

Similar products