Anti-Human C5a receptor (CD88), Biotin (clone 8D6) (rat IgG2a)

  • Catalog number
    MBS520466
  • Price
    Please ask
  • Size
    0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [C5a receptor (CD88)]
  • Products_name_syn
    [C5a receptor (CD88), Biotin (clone 8D6) (rat IgG2a); Anti-Human C5a Receptor (CD88) Monoclonal Antibody]
  • Products_gene_name
    [CD88]
  • Clonality
    Monoclonal
  • Clone
    [8D6]
  • Reactivity
    Human
  • Specificity
    CD88 (C5a Receptor) (Human C5a Receptor (CD88))
  • Form
    Biotin
  • Concentration
    0.1 mg/ml
  • Storage_stability
    Store at 4 degree C. DO NOT FREEZ PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
  • Tested_application
    Immunohistochemistry (IHC)
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Test
    MyBioSource supplies antibodies that are for research of human proteins.
  • Properties
    Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Conjugation
    Biotinylated
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Gene target
    C5a   receptor   CD88   8D6   IgG2a  
  • Gene symbol
    CD320, C5AR1
  • Short name
    Anti- C5a receptor (CD88), (clone 8D6) ( IgG2a)
  • Technique
    anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
  • Host
    Rat
  • Isotype
    Rat IGg2a, IgG2a
  • Label
    Biotin
  • Species
    Rat, Humans, Rats
  • Alternative name
    Antibody toHuman C5a receptor (CD88), biotinilated (clonality 8D6) (rat IgG2a)
  • Alternative technique
    antibodies
  • Clone name
    8D6
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    complement C5a receptor 1
  • Synonyms gene
  • Synonyms gene name
    • complement component 5 receptor 1 (C5a ligand)
    • complement component 5a receptor 1
  • Synonyms
  • Locus
  • Discovery year
    1991-12-04
  • Entrez gene record
    728
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Complement component GPCRs
    • Complement system regulators and receptors
    • CD molecules
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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