Rat Monoclonal (IgG2a) to Mouse C5AR1 / CD88 / C5a Receptor

  • Catalog number
    MBS246579
  • Price
    Please ask
  • Size
    0,05 mg
  • Other size
    please contact us to order other different size
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus, Rattus norvegicus
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    Monoclonal   IgG2a   C5AR1   CD88   C5a   Receptor  
  • Gene symbol
    C5AR1
  • Short name
    Monoclonal (IgG2a) Mouse C5AR1 / CD88 / C5a Receptor
  • Technique
    Mouse, Monoclonals or monoclonal antibodies, mouses
  • Host
    Rat
  • Isotype
    IgG2a
  • Species
    Mouse, Mouses, Rats
  • Alternative name
    Rat monoclonal (IgG2a) to Mouse complement component 5a receptor 1 / CD88 / C5a Receptor
  • Alternative technique
    murine
  • Alternative to gene target
    complement component 5a receptor 1, C5A and C5AR and C5R1 and CD88, C5AR1 and IDBG-59445 and ENSG00000197405 and 728, C5a anaphylatoxin receptor activity, Cell surfaces, C5ar1 and IDBG-146297 and ENSMUSG00000049130 and 12273, BT.34208 and IDBG-639986 and ENSBTAG00000020872 and 101908388,493645
Gene info
  • Identity
  • Gene
  • Long gene name
    complement C5a receptor 1
  • Synonyms gene
  • Synonyms gene name
    • complement component 5 receptor 1 (C5a ligand)
    • complement component 5a receptor 1
  • Synonyms
  • Locus
  • Discovery year
    1991-12-04
  • Entrez gene record
    728
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Complement component GPCRs
    • Complement system regulators and receptors
    • CD molecules
  • VEGA ID
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