AKR1C3 Inhibitor II

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Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Gene target

AKR1C3 Inhibitor
Gene symbol

AKR1C3
Short name

AKR1C3 Inhibitor II
Alternative name

aldo-keto reductase family 1, member complement component 3 (3-a hydroxysteroid dehydrogenase, classification II) suppressor II
Alternative to gene target

aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), DD3 and DDX and HA1753 and HAKRB and HAKRe and hluPGFS and HSD17B5 and PGFS, AKR1C3 and IDBG-47964 and ENSG00000196139 and 8644, oxidoreductase activity, nuclei

Identity

HGNC:386
Gene

AKR1C3
Long gene name

aldo-keto reductase family 1 member C3
Synonyms gene
- HSD17B5
Synonyms gene name
- hydroxysteroid (17-beta) dehydrogenase 5
- aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
Synonyms
- KIAA0119
- DDX
- HAKRB
- PGFS
Synonyms name
GenBank acession
- L43839
Locus

10p15.1
Discovery year

1998-09-29
Entrez gene record

8644
Pubmed identfication
- 7650035
- 9792917
RefSeq identity
- NM_003739
Classification
- Aldo-keto reductases
VEGA ID

OTTHUMG00000017585