ABIN-2 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)[ABIN-2]

• Catalog number
  MBS611483
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human, Mouse
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  ABIN-2   A-20   binding   Inhibitor   Factor-kappaB   NF-kB   Activation   [ABIN-2]  
• Gene symbol
  TNIP2, NFYB, NFE4, NFE2, TNIP3, NEFH, NFKB1, TNIP1, INA, NFASC
• Short name
  ABIN-2 (A-20 binding Inhibitor of Factor-kappaB (NF-kB) Activation)[ABIN-2]
• Technique
  activation
• Host
  Rabbit
• Alternative name
  ABIN-2 (A-20 binding suppressor on Nuclear Factor-kappaB (NF-kB) Activation)[ABIN-2]

Gene info

• Identity
  HGNC:19118
• Gene
  TNIP2
• Long gene name
  TNFAIP3 interacting protein 2
• Synonyms
  • ABIN-2
  • MGC4289
  • KLIP
  • FLIP1
• GenBank acession
  • BC002740
• Locus
  4p16.3
• Discovery year
  2002-10-03
• Entrez gene record
  79155
• Pubmed identfication
  • 11390377
  • 12933576
• RefSeq identity
  • NM_024309
• VEGA ID
  OTTHUMG00000090267

Gene info

• Identity
  HGNC:7805
• Gene
  NFYB
• Long gene name
  nuclear transcription factor Y subunit beta
• Synonyms gene name
  • nuclear transcription factor Y, beta
• Synonyms
  • CBF-A
  • HAP3
  • NF-YB
• Locus
  12q23.3
• Discovery year
  1991-11-08
• Entrez gene record
  4801
• Pubmed identfication
  • 1774067
  • 9612081
• VEGA ID
  OTTHUMG00000170176

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:19315
• Gene
  TNIP3
• Long gene name
  TNFAIP3 interacting protein 3
• Synonyms
  • LIND
  • FLJ21162
  • ABIN-3
• GenBank acession
  • AJ320534
• Locus
  4q27
• Discovery year
  2002-11-28
• Entrez gene record
  79931
• Pubmed identfication
  • 11345586
• RefSeq identity
  • NM_024873
• VEGA ID
  OTTHUMG00000132969

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:16903
• Gene
  TNIP1
• Long gene name
  TNFAIP3 interacting protein 1
• Synonyms
  • NAF1
  • KIAA0113
  • ABIN-1
  • VAN
• Synonyms name
  • virion-associated nuclear-shuttling protein
  • Nef-associated factor 1 SNP
• GenBank acession
  • AJ011895
• Locus
  5q33.1
• Discovery year
  2002-10-03
• Entrez gene record
  10318
• Pubmed identfication
  • 9923610
  • 11090181
• RefSeq identity
  • NM_006058
• VEGA ID
  OTTHUMG00000163722

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

Gene info

• Identity
  HGNC:29866
• Gene
  NFASC
• Long gene name
  neurofascin
• Synonyms gene name
  • neurofascin homolog (chicken)
• Synonyms
  • NRCAML
  • KIAA0756
  • FLJ46866
  • NF
• GenBank acession
  • AK027553
• Locus
  1q32.1
• Discovery year
  2005-11-22
• Entrez gene record
  23114
• Pubmed identfication
  • 1377696
  • 8672144
• RefSeq identity
  • NM_001005388
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000151697

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