ABIN-2 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)

• Catalog number
  MBS612361
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [ABIN-2]
• Products_name_syn
  [Anti -ABIN-2 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation)]
• Other_names
  [A20-binding inhibitor of NF-kappaB activation-2; TNFAIP3-interacting protein 2; TNFAIP3-interacting protein 2; fetal liver LKB1-interacting protein; A20-binding inhibitor of NF-kappaB activation-2; A20-binding inhibitor of NF-kappa-B activation 2; TNFAIP3 interacting protein 2; A20-binding inhibitor of NF-kappa-B activation 2; ABIN-2; Fetal liver LKB1-interacting protein]
• Other_gene_names
  [TNIP2; TNIP2; KLIP; ABIN2; FLIP1; ABIN2; FLIP1; ABIN-2]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes human ABIN-2. Species Crossreactivity: mouse.
• Purity
  Affinity Purified Purified by Protein G chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  Western Blot (WB)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  ABIN-2   A-20   binding   Inhibitor   Factor-kappaB   NF-kB   Activation  
• Gene symbol
  NFYB, NFE4, NFE2, NEFH, NFKB1, INA, NFASC, NFATC1, NFYC, NFATC2
• Short name
  ABIN-2 (A-20 binding Inhibitor of Factor-kappaB (NF-kB) Activation)
• Technique
  activation
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  ABIN-2 (A-20 binding suppressor on Nuclear Factor-kappaB (NF-kB) Activation)

Gene info

• Identity
  HGNC:7805
• Gene
  NFYB
• Long gene name
  nuclear transcription factor Y subunit beta
• Synonyms gene name
  • nuclear transcription factor Y, beta
• Synonyms
  • CBF-A
  • HAP3
  • NF-YB
• Locus
  12q23.3
• Discovery year
  1991-11-08
• Entrez gene record
  4801
• Pubmed identfication
  • 1774067
  • 9612081
• VEGA ID
  OTTHUMG00000170176

Gene info

• Identity
  HGNC:29902
• Gene
  NFE4
• Long gene name
  nuclear factor, erythroid 4
• Synonyms
  • NF-E4
• Locus
  7q22.1
• Discovery year
  2013-08-23
• Entrez gene record
  58160
• Pubmed identfication
  • 11003662
• RefSeq identity
  • NR_166510
• VEGA ID
  OTTHUMG00000157208

Gene info

• Identity
  HGNC:7780
• Gene
  NFE2
• Long gene name
  nuclear factor, erythroid 2
• Synonyms gene name
  • nuclear factor (erythroid-derived 2), 45kD
  • nuclear factor (erythroid-derived 2), 45kDa
• Synonyms
  • NF-E2
• GenBank acession
  • BC005044
• Locus
  12q13.13
• Discovery year
  1993-11-03
• Entrez gene record
  4778
• Pubmed identfication
  • 8355703
• RefSeq identity
  • NM_006163
• Classification
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000169761

Gene info

• Identity
  HGNC:7737
• Gene
  NEFH
• Long gene name
  neurofilament heavy chain
• Synonyms gene name
  • neurofilament, heavy polypeptide 200kDa
  • neurofilament heavy polypeptide
  • neurofilament heavy
• Synonyms
  • NF-H
  • NFH
• Locus
  22q12.2
• Discovery year
  1988-08-31
• Entrez gene record
  4744
• RefSeq identity
  • NM_021076
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000151155
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Gene info

• Identity
  HGNC:7794
• Gene
  NFKB1
• Long gene name
  nuclear factor kappa B subunit 1
• Synonyms gene name
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• Synonyms
  • KBF1
  • p105
  • NFKB-p50
  • p50
  • NF-kappaB
  • NFkappaB
  • NF-kB1
• Synonyms name
  • Nuclear factor NF-kappa-B p105 subunit
• GenBank acession
  • M58603
• Locus
  4q24
• Discovery year
  1991-11-14
• Entrez gene record
  4790
• Pubmed identfication
  • 1992489
• RefSeq identity
  • NM_003998
• Classification
  • NF-kappa B complex subunits
  • Ankyrin repeat domain containing
  • IPT domain containing
• VEGA ID
  OTTHUMG00000161080
• Locus Specific Databases
  • LRG_1316

Gene info

• Identity
  HGNC:6057
• Gene
  INA
• Long gene name
  internexin neuronal intermediate filament protein alpha
• Synonyms gene
  • NEF5
• Synonyms gene name
  • internexin neuronal intermediate filament protein, alpha
• Synonyms
  • NF-66
• GenBank acession
  • S78296
• Locus
  10q24.33
• Discovery year
  1999-03-24
• Entrez gene record
  9118
• Pubmed identfication
  • 7769995
• RefSeq identity
  • NM_032727
• Classification
  • Intermediate filaments Type IV
• VEGA ID
  OTTHUMG00000018986

Gene info

• Identity
  HGNC:29866
• Gene
  NFASC
• Long gene name
  neurofascin
• Synonyms gene name
  • neurofascin homolog (chicken)
• Synonyms
  • NRCAML
  • KIAA0756
  • FLJ46866
  • NF
• GenBank acession
  • AK027553
• Locus
  1q32.1
• Discovery year
  2005-11-22
• Entrez gene record
  23114
• Pubmed identfication
  • 1377696
  • 8672144
• RefSeq identity
  • NM_001005388
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000151697

Gene info

• Identity
  HGNC:7775
• Gene
  NFATC1
• Long gene name
  nuclear factor of activated T cells 1
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
  • nuclear factor of activated T-cells 1
• Synonyms
  • NF-ATC
  • NFATc
  • NFAT2
• GenBank acession
  • U08015
• Locus
  18q23
• Discovery year
  1994-11-16
• Entrez gene record
  4772
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_172390
• Classification
  • Nuclear factors of activated T-cells
  • IPT domain containing
• VEGA ID
  OTTHUMG00000132897

Gene info

• Identity
  HGNC:7806
• Gene
  NFYC
• Long gene name
  nuclear transcription factor Y subunit gamma
• Synonyms gene name
  • nuclear transcription factor Y, gamma
• Synonyms
  • CBF-C
  • NF-YC
• GenBank acession
  • U78774
• Locus
  1p34.2
• Discovery year
  1996-10-26
• Entrez gene record
  4802
• Pubmed identfication
  • 8921405
  • 9249075
• RefSeq identity
  • NM_014223
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000007729

Gene info

• Identity
  HGNC:7776
• Gene
  NFATC2
• Long gene name
  nuclear factor of activated T cells 2
• Synonyms gene name
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T-cells 2
• Synonyms
  • NF-ATP
  • NFATp
  • NFAT1
• GenBank acession
  • U43342
  • U43341
• Locus
  20q13.2
• Discovery year
  1994-11-16
• Entrez gene record
  4773
• Pubmed identfication
  • 8202141
• RefSeq identity
  • NM_012340
• Classification
  • IPT domain containing
  • Nuclear factors of activated T-cells
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000032747

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