Mutant IDH1 inhibitor
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Catalog numberHY-13972
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PricePlease ask
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Size10mg
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Alternative_NamesNA
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CAS1429180-08-4
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MWt466.58
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FormulaC25H34N6O3
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SolubilityDMSO: ≥ 34 mg/mL
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Clinical_InformationNo Development Reported
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PathwayMetabolic Enzyme/Protease
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TargetIsocitrate Dehydrogenase (IDH)
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DescriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolIDH1, IDH1-AS1
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Short nameMutant IDH1 inhibitor
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Alternative nameMutant IDH1 suppressor
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Gene info
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Identity
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Gene
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Long gene nameisocitrate dehydrogenase (NADP(+)) 1
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Synonyms gene name
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase 1 (NADP+)
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- Isocitrate dehydrogenases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameIDH1 antisense RNA 1
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Synonyms gene name
- IDH1 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2012-02-24
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Entrez gene record
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Classification
- Antisense RNAs
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VEGA ID