Mutant IDH1 inhibitor 50mg

Alternative_Names

NA
CAS

1429180-08-4
Purity

>98%
MWt

466.58
Formula

C25H34N6O3
Solubility

DMSO : ≥ 34 mg/mL (72.87 mM)
Clinical_Information

No Development Reported
Pathway

Metabolic Enzyme/Protease
Target

Isocitrate Dehydrogenase (IDH)
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:5382
Gene

IDH1
Long gene name

isocitrate dehydrogenase (NADP(+)) 1
Synonyms gene name
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase 1 (NADP+)
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic
Locus

2q34
Discovery year

2001-06-22
Entrez gene record

3417
RefSeq identity
- NM_005896
Classification
- Isocitrate dehydrogenases
VEGA ID

OTTHUMG00000132943
Locus Specific Databases
- LRG_610