PAb (IgG) to Sheep YWHAE / 14-3-3 Epsilon
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Catalog numberMBS244175
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PricePlease ask
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Size0.05 ml
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Alternative name1Anti-Rabbit Polyclonal (IgG) to Sheep YWHAE / 14-3-3 Epsilon
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Alternative name2Rabbit PAb (IgG) to Ovine YWHAE / 14-3-3 Epsilon
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Alternative name3Lapin Polyclonal (IgG) to Ovinae YWHAE / 14-3-3 Epsilon
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Alternative name4YWHAE / 14-3-3 Epsilon
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Alternative name5Anti-YWHAE / 14-3-3 Epsilon Antibody (N-Terminus) IHC-plus; YWHAE; 14-3-3E; 14-3-3 epsilon; 14-3-3 protein epsilon; MDCR; MDS; KCIP-1; Sheep YWHAE; 14-3-3 Epsilon
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Other names14-3-3 protein epsilon; 14-3-3 protein epsilon; 14-3-3 protein epsilon; 14-3-3 epsilon; epididymis luminal protein 2; protein kinase C inhibitor protein-1; mitochondrial import stimulation factor L subunit; tyrosine 3/tryptophan 5 -monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon; N/A
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Gene nameYWHAE
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Gene name synonimsN/A
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Other gene namesYWHAE; YWHAE; MDS; HEL2; MDCR; KCIP-1; 14-3-3E; 14-3-3E
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypeIgG
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ClonePolyclonal antibody
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Host organismRabbit
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Species reactivityBovine, Chicken, Human, Mouse, Rabbit, Rat, Sheep Predicted Reactivity: Mammal (at least 90% immunogen sequence identity)
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Specificity and cross reactivityRecognizes the acetylated N-terminal of 14-3-3 epsilon. It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 epsilon is expressed in all mammals. It is deleted in small cell lung cancers disrupting the G(2) checkpoint. During apoptosis, cleavage of 14-3-3 protein by caspase-3 increases the affinity between bad and Bcl-x(L). When bound by ERK, 14-3-3 epsilon is thought to deactivate heat shock factor 1 in cells recovering from heat shock. It is also a potential suicide susceptibility gene. May not react with recombinant proteins that are not N-acetylated.
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Purification methodN/A
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Form AppearanceSerum, 0.09% sodium azide.
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ConcentrationN/A
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Storage and shipping+Store productone at +4 degrees Celsius. or Store productone at -20 degrees Celsius., Avoid repeated freezing and thawing.
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Tested forImmunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
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Gene target
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Gene symbolYWHAQ, YWHAG, YWHAZ, MIR1302-3, MIR509-3, MIR7-3, PIRC13, PIRC11
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Short namePAb (IgG) YWHAE / 14-3-3 Epsilon
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TechniqueIgG, IgGs
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HostSheep
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IsotypeIgG, IgG
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SpeciesSheep, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
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Alternative namepolyclonal (Immunoglobulin G) to ovine tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide / 14-3-3 Epsilon
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Alternative techniqueimmunoglobulins
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Alternative to gene targettyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, 14-3-3E and HEL2 and KCIP-1 and MDCR and MDS, YWHAE and IDBG-14629 and ENSG00000108953 and 7531, phosphoprotein binding, Plasma membranes, Ywhae and IDBG-200597 and ENSMUSG00000020849 and 22627, YWHAE and IDBG-632682 and ENSBTAG00000005664 and 282125
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Gene info
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Identity
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Gene
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Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
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Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
- protein, theta
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-08-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
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Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-09-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
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Synonyms gene
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Synonyms gene name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-09-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 14-3-3 phospho-serine/phospho-threonine binding proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-3
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 13
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 11
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
