Anti-BCL-2 BINDING COMPONENT 3
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Catalog numberMBS221697
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PricePlease ask
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Size100ug
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Alternative name1Anti-RABBIT ANTI BCL-2 BINDING COMPONENT 3
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Alternative name2RABBIT ANTI BCL-2 BINDING COMPONENT 3
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Alternative name3Lapin ANTI BCL-2 BINDING COMPONENT 3
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Alternative name4BCL-2 BINDING COMPONENT 3
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Alternative name5N/A
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Other namesbcl-2-binding component 3 isoform 1; Bcl-2-binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; BCL2 binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
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Gene nameN/A
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Gene name synonimsN/A
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Other gene namesBBC3; BBC3; JFY1; PUMA; JFY-1; PUMA
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CategoryAntibodies
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ClonalityPolyclonal
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Immunoglobulin isotypePolyclonal IgG
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ClonePolyclonal antibody
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Host organismRabbit
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Species reactivityHuman
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Specificity and cross reactivityBCL-2 BINDING COMPONENT 3 This item recognises the p53 - upregulated modulator of apoptosis (PUMA), also known as Bcl-2 binding component 3. Bcl-2 binding component 3 is a pro-apoptotic member of the BCL-2 family. _x000D__x000D_Bcl-2 binding component 3 is localised to the mitochondria, binds BCL-2 and induces cytochrome C release and apoptosis in response to p53.
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Purification methodN/A
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Form AppearancePurified (Purified IgG - liquid)
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ConcentrationIgG concentration 1.0 mg/ml
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Storage and shippingStore at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
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Tested forWestern Blot (WB), Immunohistology - Paraffin (IHC)
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Descriptionproductone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
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AdvisoryIn order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Gene target
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Gene symbolBCL2, BCL2L1, BCL2L13, BCL2L10, BCL2L14, BCL2L2, MIR1289-2, MIR521-2, MIR509-2, MIR512-2
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Short nameAnti-BCL-2 BINDING COMPONENT 3
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Techniqueanti-, anti, antibody to, antibodies
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Alternative nameAntibody toBCL-2 BINDING COMPONENT 3
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameBCL2 apoptosis regulator
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Synonyms gene name
- B-cell CLL/lymphoma 2
- BCL2, apoptosis regulator
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-10-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 13
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Synonyms gene name
- BCL2-like 13 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-09-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 10
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Synonyms gene name
- BCL2-like 10 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-05-21
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Entrez gene record
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Pubmed identfication
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Classification
- BCL2 family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 14
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Synonyms gene name
- BCL2-like 14 (apoptosis facilitator)
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-02-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameBCL2 like 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-07-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 509-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data