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Also known as
Urokinase Plasminogen Activator Receptor
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Other names
urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor; Monocyte activation antigen Mo3
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR
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Gene name synonims
PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR
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Other gene names
PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2A
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Clone
8B50
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Host organism
Rat (Rattus norvegicus)
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Source organism
Mouse (Mus musculus)
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Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes mouse uPAR. Does not cross-react with rhuPAR in direct ELISAs or Western Blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein G affinity chromatography. Endotoxin:
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Form Appearance
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
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Concentration
N/A
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Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Reconstitute to nominal volume by adding sterile buffer. Aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
