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Products_type
Antibody
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Products_short_name
[Urokinase Plasminogen Activator Receptor]
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Products_name_syn
[Anti -Urokinase Plasminogen Activator Receptor (uPAR, CD87)]
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Other_names
[urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor; Monocyte activation antigen Mo3]
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Other_gene_names
[PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR]
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Clonality
Monoclonal
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Clone
[9B17]
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Reactivity
Human
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Specificity
Recognizes an epitope on domain 3 of human uPAR. No cross-reactivity is observed with murine uPAR, human uPA, human tPA or human PAI-1.
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Purity
Affinity Purified Purified by Protein A/G affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.