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Also known as
TREM-2b
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Other names
triggering receptor expressed on myeloid cells 2; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2; OTTHUMP00000016368; OTTHUMP00000016369; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
TREM2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c; N/A
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Gene name synonims
TREM2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c; N/A
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Other gene names
TREM2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG2b
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Clone
7H10-1
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Host organism
Rat (Rattus norvegicus)
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Source organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes mouse TREM-2b. Species Crossreactivity: human; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein G affinity chromatography.
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Form Appearance
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 1ml sterile PBS.
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Concentration
N/A
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Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested applications
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
