TREM-2b (Trem2, Triggering Receptor Expressed on Monocytes 2)
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Catalog numberMBS604718
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Price:
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Size5x0.5 mg
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Products_typeAntibody
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Products_short_name[TREM-2b]
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Products_name_syn[Anti -TREM-2b (Trem2, Triggering Receptor Expressed on Monocytes 2)]
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Other_names[triggering receptor expressed on myeloid cells 2; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2; OTTHUMP00000016368; OTTHUMP00000016369; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2]
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Other_gene_names[TREM2; TREM2; TREM-2; Trem2a; Trem2b; Trem2c]
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ClonalityMonoclonal
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Clone[7H10-1]
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ReactivityHuman, Mouse
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SpecificityRecognizes mouse TREM-2b. Species Crossreactivity: human
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 1ml sterile PBS.
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Storage_stabilityLyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolTREM1, TREM2
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Short nameTREM-2b (Trem2, Triggering Receptor Expressed on Monocytes 2)
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HostRat
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IsotypeIgG2b
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Alternative nameTREM-2b (triggering receptor expressed on myeloid cells 2, Triggering Receptor Expressed on Monocytes 2)
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Alternative to gene targettriggering receptor expressed on myeloid cells 2, TREM2 and IDBG-86566 and ENSG00000095970 and 54209, scaffold protein binding, Extracellular, Trem2 and IDBG-189871 and ENSMUSG00000023992 and 83433, TREM2 and IDBG-630863 and ENSBTAG00000007275 and 506467
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Gene info
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Identity
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Gene
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Long gene nametriggering receptor expressed on myeloid cells 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametriggering receptor expressed on myeloid cells 2
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Synonyms gene name
- triggering receptor expressed on myeloid cells 2a
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-08-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
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VEGA ID
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Locus Specific Databases