RUNX1 (Runt-related Transcription Factor 1, Acute Myeloid Leukemia 1, Acute Myeloid Leukemia 1 Protein, Alpha Subunit Core Binding Factor, AML-1, AML1 EVI-1, AML1 Oncogene, AMLCR1, Core Binding Factor alpha 2 Subunit, CBF-alpha-2, CBFA2, Core Binding Fact Antibody

  • Catalog number
    GEN632699
  • Price
    Please ask
  • Size
    100ul
  • Also known as
    RUNX1
  • Other names
    RUNX1 protein; RUNX1 protein; runt-related transcription factor 1; CBF-alpha-2; PEA2-alpha B; PEBP2-alpha B; aml1 oncogene; oncogene AML-1; OTTHUMP00000108696; OTTHUMP00000108697; OTTHUMP00000108699; OTTHUMP00000108700; OTTHUMP00000108702; AML1-EVI-1 fusion protein; acute myeloid leukemia 1 protein; core-binding factor subunit alpha-2; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit; core-binding factor, runt domain, alpha subunit 2; polyomavirus enhancer-binding protein 2 alpha B subunit; runt-related transcription factor 1; N/A
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    RUNX1; RUNX1; AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; N/A
  • Gene name synonims
    RUNX1; RUNX1; AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; N/A
  • Other gene names
    RUNX1; RUNX1; AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1; N/A
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG
  • Clone
    9H504
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes human RUNX1. Species Crossreactivity: Mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Supernatant
  • Form Appearance
    Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide and 0.05% BSA.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested applications
    Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
  • Description
    The RUNX1 (Runt- Transcription Factor 1, Acute Myeloid Leukemia 1, Acute Myeloid Leukemia 1 Protein, Alpha Subunit Core Binding Factor, AML-1, AML1 EVI-1, AML1 Oncogene, AMLCR1, Core Binding Factor alpha 2 Subunit, CBF-alpha-2, CBFA2, Core Binding Fact Antibody is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
  • Properties
    If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    RUNX1   Runt-related   Transcription   Factor   Acute   Myeloid   Leukemia   Acute   Myeloid   Leukemia   Protein   Alpha   Subunit   Core   Binding   Factor   AML-1   AML1   EVI-1   AML1   Oncogene   AMLCR1   Core   Binding   Factor   alpha   Subunit   CBF-alpha-2   CBFA2   Core   Binding   Fact  
  • Gene symbol
    RUNX1, NFYC, NFYB, NFYA, MECOM, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1
  • Short name
    RUNX1 (Runt- Transcription Factor 1, Acute Myeloid Leukemia 1, Acute Myeloid Leukemia 1 Protein, Alpha Subunit Core Binding Factor, AML-1, AML1 EVI-1, AML1 Oncogene, AMLCR1, Core Binding Factor alpha 2 Subunit, CBF-alpha-2, CBFA2, Core Binding Fact Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    Anti-RUNX1 (Runt-related Transcription Factor 1, Acute Myeloid Leukemia 1, Acute Myeloid Leukemia 1 Protein, Alpha Subunit Core Binding Factor, AML-1, AML1 EVI-1, AML1 Oncogene, AMLCR1, Core Binding Factor alpha 2 Subunit, CBF-alpha-2, CBFA2, Core Binding Fact
  • Alternative technique
    antibodies
  • Alternative to gene target
    runt-related transcription factor 1, AML1 and AML1-EVI-1 and AMLCR1 and CBFA2 and EVI-1 and PEBP2aB, RUNX1 and IDBG-2825 and ENSG00000159216 and 100506403,101928269,861, repressing transcription factor binding, nuclei, Runx1 and IDBG-177713 and ENSMUSG00000022952 and 12394, RUNX1 and IDBG-640443 and ENSBTAG00000004742 and 529631
  • Virus
    leukemia
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:5670
  • Gene
    IGHVII-1-1
  • Long gene name
    immunoglobulin heavy variable (II)-1-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-1-1
    • immunoglobulin heavy variable (II)-1-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
    14q32.33
  • Discovery year
    2000-04-17
  • Entrez gene record
    28377
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
    OTTHUMG00000152325
Gene info
Gene info
  • Identity
    HGNC:50820
  • Gene
    TRUND-NNN8-1
  • Long gene name
    tRNA-undetermined (NNN) 8-1
  • Synonyms gene name
    • transfer RNA-undetermined (NNN) 8-1
  • GenBank acession
  • Locus
    1
  • Discovery year
    2014-06-20
  • Entrez gene record
    103482528
  • Pubmed identfication
Gene info
  • Identity
    HGNC:50819
  • Gene
    TRUND-NNN7-1
  • Long gene name
    tRNA-undetermined (NNN) 7-1
  • Synonyms gene name
    • transfer RNA-undetermined (NNN) 7-1
  • GenBank acession
  • Locus
    1
  • Discovery year
    2014-06-20
  • Entrez gene record
    103482531
  • Pubmed identfication
Gene info
  • Identity
    HGNC:5760
  • Gene
    IGKV1OR2-1
  • Long gene name
    immunoglobulin kappa variable 1/OR2-1 (pseudogene)
  • Synonyms gene
  • Synonyms gene name
    • immunoglobulin kappa variable 1/OR-1
    • immunoglobulin kappa variable 1/OR-1 pseudogene
    • immunoglobulin kappa variable 1/OR-1 (pseudogene)
  • Synonyms
  • GenBank acession
  • Locus
    2p11.1
  • Discovery year
    2000-04-18
  • Entrez gene record
    3531
  • Pubmed identfication
  • Classification
    • Immunoglobulin kappa (IGK) orphons
  • VEGA ID
    OTTHUMG00000155081
MeSH Data
  • Name
    Blotting, Western
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
RUNX1 Runt Transcription Factor 1 Acute Myeloid Leukemia 1 A
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