RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia Gene 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen
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Catalog numberMBS607322
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Price819.05 USD
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Size0.1 mg
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Products_typeAntibody
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Products_short_name[RUNX3]
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Products_name_syn[Anti -RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia Gene 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen]
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Other_names[runt-related transcription factor 3 isoform 2; Runt-related transcription factor 3; runt-related transcription factor 3; CBF-alpha-3; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; oncogene AML-2; OTTHUMP00000003370; OTTHUMP00000003371; transcription factor AML2; acute myeloid leukemia gene 2; acute myeloid leukemia 2 protein; core-binding factor subunit alpha-3; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; core-binding factor, runt domain, alpha subunit 3; polyomavirus enhancer-binding protein 2 alpha C subunit; runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit]
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Other_gene_names[RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3]
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ClonalityMonoclonal
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Clone[9j77]
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ReactivityHuman
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SpecificityRecognizes human RUNX3.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationWestern Blot (WB)
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DescriptionThe RUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbolRUNX3, NFYC, NFYB, NFYA, RUNX3-AS1, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2
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Short nameRUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen
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HostMouse
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IsotypeIgG1
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Alternative namerunt-related transcription factor 3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia Gene 2, AML2, AML-2, Core Binding Factor a 3 functionnal sequence, Core Binding Factor Runt Domain a functionnal sequence 3, CBF-a-3, CBFA3, FLJ34510, MGC16070, Oncogen
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Alternative to gene targetrunt-related transcription factor 3, AML2 and CBFA3 and PEBP2aC, RUNX3 and IDBG-94257 and ENSG00000020633 and 864, ATP binding, nuclei, Runx3 and IDBG-196773 and ENSMUSG00000070691 and 12399, RUNX3 and IDBG-645327 and ENSBTAG00000019800 and 617389
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Virusleukemia
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Gene info
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Identity
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Gene
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Long gene nameRUNX family transcription factor 3
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Synonyms gene
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Synonyms gene name
- runt-related transcription factor 3
- runt related transcription factor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-11-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Runt-related transcription factors
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit gamma
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Synonyms gene name
- nuclear transcription factor Y, gamma
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit beta
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Synonyms gene name
- nuclear transcription factor Y, beta
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Synonyms
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Locus
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Discovery year1991-11-08
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenuclear transcription factor Y subunit alpha
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Synonyms gene name
- nuclear transcription factor Y, alpha
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Synonyms
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Locus
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Discovery year1991-11-08
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRUNX3 antisense RNA 1
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Locus
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Discovery year2020-03-19
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Entrez gene record
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene namemicroRNA 7-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR7 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 329-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-11
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR329 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 512-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR506 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 521-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2005-07-15
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR515 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-2
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
MeSH Data
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Name
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ConceptScope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
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Tree numbers
- C04.557.337.372
- C04.619.531
- E05.598.500.496.500
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Qualifiersdiagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery