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Also known as
Parathyroid Hormone/Parathyroid Hormone Related Protein Receptor
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Other names
parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1 receptor; PTH/PTHr receptor; OTTHUMP00000164784; OTTHUMP00000209970; OTTHUMP00000209971; OTTHUMP00000209972; OTTHUMP00000209973; PTH/PTHrP type I receptor; parathyroid hormone receptor 1; seven transmembrane helix receptor; parathyroid hormone/parathyroid hormone-related protein receptor; parathyroid hormone 1 receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
PTH1R; PTH1R; PFE; PTHR; PTHR1; MGC138426; MGC138452; PTHR; PTHR1
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Gene name synonims
PTH1R; PTH1R; PFE; PTHR; PTHR1; MGC138426; MGC138452; PTHR; PTHR1
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Other gene names
PTH1R; PTH1R; PFE; PTHR; PTHR1; MGC138426; MGC138452; PTHR; PTHR1
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1,k
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Clone
0.T.125
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Porcine; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes human PTH/PTHrP receptor, MW 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor. Species Crossreactivity: mouse and porcine. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Affinity Purified by Protein G affinity chromatography.
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Form Appearance
Supplied as a liquid in PBS, pH 7.6, 0.07% sodium azide, 30% glycerol.
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
Western Blot (WB), Immunohistochemistry (IHC)
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Description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
