Parathyroid Hormone/Parathyroid Hormone Related Protein Receptor (PTH/PTHrP Receptor)
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Catalog numberMBS602411
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Price:Ask for price
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Size5x0.2 mg
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Products_typeAntibody
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Products_short_name[Parathyroid Hormone/Parathyroid Hormone Related Protein Receptor]
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Products_name_syn[Anti -Parathyroid Hormone/Parathyroid Hormone Related Protein Receptor (PTH/PTHrP Receptor)]
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Other_names[parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1 receptor; PTH/PTHr receptor; OTTHUMP00000164784; OTTHUMP00000209970; OTTHUMP00000209971; OTTHUMP00000209972; OTTHUMP00000209973; PTH/PTHrP type I receptor; parathyroid hormone receptor 1; seven transmembrane helix receptor; parathyroid hormone/parathyroid hormone-related protein receptor; parathyroid hormone 1 receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor]
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Other_gene_names[PTH1R; PTH1R; PFE; PTHR; PTHR1; MGC138426; MGC138452; PTHR; PTHR1]
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ClonalityMonoclonal
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Clone[0.T.125]
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ReactivityHuman, Mouse, Porcine
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SpecificityRecognizes human PTH/PTHrP receptor, MW 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor. Species Crossreactivity: mouse and porcine.
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PurityAffinity Purified Purified by Protein G affinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.6, 0.07% sodium azide, 30% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_applicationWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionHormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolPTH
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Short nameParathyroid Hormone/Parathyroid Hormone Protein Receptor (PTH/PTHrP Receptor)
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HostMouse
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IsotypeIgG1,k
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Alternative nameParathyroid Hormone/Parathyroid Hormone Related Protein Receptor (parathyroid hormone/PTHrP Receptor)
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Alternative to gene targetparathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903
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Gene info
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Identity
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Gene
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Long gene nameparathyroid hormone
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
