-
Also known as
SOD1 / SOD
-
Other names
superoxide dismutase; Superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; epididymis secretory protein Li 44; superoxide dismutase 1, soluble; Superoxide dismutase 1; hSod1
-
Category
Antibodies
-
Subcategory
Mnoclonal antibodies
-
Gene name
SOD1
-
Gene name synonims
SOD
-
Other gene names
SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1
-
Clonality
Monoclonal
-
Immunoglobulin isotype
IgG1
-
Clone
2F5
-
Host organism
Mouse (Mus musculus)
-
Species reactivity
Bovine, Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivity
Recognizes copper/zinc superoxide dismutase (SOD). Superoxide dismutases are ubiquitous metalloproteins that destroy oxygen-mediated free radicals, that are normally produced within the cells, which are toxic to biological systems. There are three forms of superoxide dismutase, including the Fe, mitochondrial (Mn) and the copper/zinc binding (Cu/Zn) form. The Cu/Zn form of SOD is utilized by most eukaryotic organisms. SOD Cu/Zn prevents oxygen-mediated free radical damage by catalyzing the dismutation of the toxic superoxide radical to molecular oxygen and hydrogen peroxide. Does not cross react with immunoglobulins but does react weakly with Mn SOD; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification method
Protein G Purified
-
Form Appearance
PBS with 0.1% sodium azide and 0.1% BSA. Sourced in TCS.
-
Concentration
1 miligram per 1 mililiter
-
Storage and shipping
For short term storage keep the antibody at +4 degrees Celsius. For longer storage the antibody should be kept at -20 degrees Celsius. Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity.
-
Tested applications
Immunohistochemistry (IHC - Paraffin; IHC - Frozen), ELISA (EIA)
-
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus
-
French translation
anticorps
-
Gene target
-
Gene symbol
SOD1-DT, SOD3, SOD1
-
Short name
Mouse Monoclonal [clone 2F5] (IgG1) SOD1 / SOD Antibody
-
Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
-
Host
mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
-
Isotype
IgG1
-
Species
Bovine, Bos Taurus genes are available form the Bovine Genome database. Mouses
-
Alternative name
Anti-Mouse Monoclonal [clone 2F5] (IgG1) to Bovine SOD1 / SOD
-
Alternative technique
antibodies, murine
-
Alternative to gene target
superoxide dismutase 1, soluble, ALS and ALS1 and HEL-S-44 and homodimer and hSod1 and IPOA and SOD, SOD1 and IDBG-1609 and ENSG00000142168 and 6647, chaperone binding, nuclei, Sod1 and IDBG-174662 and ENSMUSG00000022982 and 20655
-
Clone name
2F5
-
