MOUSE Anti-HUMAN HIF1 ALPHA Antibody
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Catalog numberGEN219821
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Price:
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Size100ug
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Also known asHIF1 ALPHA
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Other nameshypoxia-inducible factor 1-alpha isoform 3; Hypoxia-inducible factor 1-alpha; hypoxia-inducible factor 1-alpha; HIF-1-alpha; member of PAS protein 1; ARNT interacting protein; ARNT-interacting protein; member of PAS superfamily 1; hypoxia-inducible factor1alpha; PAS domain-containing protein 8; basic-helix-loop-helix-PAS protein MOP1; class E basic helix-loop-helix protein 78; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameHIF1 ALPHA
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Gene name synonimsN/A
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Other gene namesHIF1A; HIF1A; HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; BHLHE78; MOP1; PASD8; HIF-1-alpha; HIF1-alpha; bHLHe78
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG2a
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CloneHalpha111a
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityHIF1 ALPHA This item specifically recognizes human HIF1 alpha (HIF1A), otherwise known as Hypoxia-inducible factor 1-alpha, a widely expressed bHLH-PAS transcription factor, which acts as a critical regulatory protein in the host response to oxygen depravation (hypoxia). _x000D__x000D_HIF1A and HIF1B (HIF1 beta/ARNT) form the highly-conserved heterodimeric HIF-1 transcriptional complex. During hypoxic conditions, HIF1A accumulates in the nucleus and activates the transcription of many genes encoding proteins involved in the production of oxygen delivery and metabolic adaptation, such as vascular endothelial growth factor (VEGF) and glucose transporters. Under normal oxygen conditions, HIF1A is targeted by HIF prolyl-hydroxylase, followed by rapid protease degradation, which is inhibited during hypoxia. _x000D__x000D_Overexpression of HIF1A occurs in many common human cancers, including pancreatic, bladder and renal carcinomas.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodN/A
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Form AppearancePurified (Purified IgG - liquid)
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ConcentrationIgG concentration 1.0mg/ml
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Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from the date of dispatch.
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Tested applicationsImmunohistology - Paraffin (IHC)
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DescriptionThe MOUSE Anti- HIF1 ALPHA Antibody is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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TestMBS Monoclonals supplies antibodies that are for research of human proteins. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolSRPRA, CBX5, AGPAT1, DRAP1, SCART1, TUBA3D, HIF1A, CTNNAL1, TLK2, CAMK1
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Short nameMOUSE Anti- HIF1 ALPHA Antibody
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Techniqueanti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
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Hostmouse
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-MOUSE ANTI HUMAN HIF1 ALPHA
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameSRP receptor subunit alpha
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Synonyms gene
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Synonyms gene name
- signal recognition particle receptor (docking protein)
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namechromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name1-acylglycerol-3-phosphate O-acyltransferase 1
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Synonyms gene name
- 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- 1-acylglycerol-3-phosphate O-acyltransferases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameDR1 associated protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-09-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namescavenger receptor family member expressed on T cells 1
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Synonyms gene name
- scavenger receptor family member expressed on T-cells 1
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Synonyms
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Locus
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Discovery year2017-02-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptor cysteine rich domain containing
Gene info
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Identity
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Gene
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Long gene nametubulin alpha 3d
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2007-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tubulins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehypoxia inducible factor 1 subunit alpha
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Synonyms gene name
- hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic helix-loop-helix proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecatenin alpha like 1
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Synonyms gene name
- catenin (cadherin-associated protein), alpha-like 1
- catenin alpha-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametousled like kinase 2
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Synonyms gene name
- tousled-like kinase 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-01-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecalcium/calmodulin dependent protein kinase I
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-10-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Calmodulin dependent protein kinases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data