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Also known as
Epidermal Growth Factor Receptor Receptor
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Other names
epidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Gene name synonims
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
3i13
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Host organism
Mouse (Mus musculus)
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Source organism
Human (Homo sapiens)
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Species reactivity
Human (Homo sapiens), Monkey, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
Recognizes overexpressed levels of human EGF receptor only when phosphorylated at Tyr1068. Does not recognize other sites of tyrosine phosphorylation on EGF receptor, nor does it crossreact with other tyrosine-phosphorylated proteins. Species crossreactivity: rat and monkey.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
Ascites Ascites
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Form Appearance
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
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Concentration
N/A
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Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applications
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
EGFR, EGFR-AS1, EGILA, RHBDF1
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Short name
Epidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor , ERBB, ERBB1, HER1, mENA, PIG61, Rece
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Alternative name
Anti-Epidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor precursor, ERBB, ERBB1, HER1, mENA, PIG61, Rece
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Alternative to gene target
epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Virus
leukemia
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