a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI)
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Catalog numberGEN603088
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PricePlease ask
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Size500ug
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Also known asa1-Antitrypsin
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Other namesalpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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Gene name synonimsSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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Other gene namesSERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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Clone8.F.14
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Host organismMouse (Mus musculus)
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Source organismHuman (Homo sapiens)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human alpha-1-Antitrypsin. No crossreactivity with alpha-1-antichymotrypsin.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodChromatographically purified
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Form AppearanceSupplied as a liquid in PBS, pH 7.5. No preservative added.
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ConcentrationN/A
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Storage and shippingStore the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested applicationsELISA (EL/EIA)
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DescriptionThe a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI) is a α- or alpha protein sometimes glycoprotein present in blood. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolTRI-AAT1-1, SLC33A1, NBN, TRI-AAT4-1, TRI-AAT7-1, TRI-AAT12-1, TRI-AAT3-1, TRI-AAT11-1, TRI-AAT2-1, TRI-AAT6-1
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Short namea1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI)
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Alternative nameAnti-a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI)
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Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 1-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 12 (anticodon AAU)
- transfer RNA-Ile (AAT) 1-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 33 member 1
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Synonyms gene
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Synonyms gene name
- acetyl-Coenzyme A transporter
- spastic paraplegia 42 (autosomal dominant)
- solute carrier family 33 (acetyl-CoA transporter), member 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-02-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenibrin
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Synonyms gene
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Synonyms gene name
- Nijmegen breakage syndrome 1 (nibrin)
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MRN complex
- BRCA1 C complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 4-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 24 (anticodon AAU)
- transfer RNA-Ile (AAT) 4-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 7-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 8 (anticodon AAU)
- transfer RNA-Ile (AAT) 7-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 12-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 30 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 12-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 3-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 11 (anticodon AAU)
- transfer RNA-Ile (AAT) 3-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 11-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 29 (anticodon AAU) pseudogene
- transfer RNA-Ile (AAT) 11-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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RefSeq identity
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Classification
- Cytoplasmic transfer RNA pseudogenes
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 2-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 4 (anticodon AAU)
- transfer RNA-Ile (AAT) 2-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
Gene info
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Identity
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Gene
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Long gene nametRNA-Ile (anticodon AAT) 6-1
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Synonyms gene
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Synonyms gene name
- transfer RNA isoleucine 22 (anticodon AAU)
- transfer RNA-Ile (AAT) 6-1
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Synonyms
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GenBank acession
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Locus
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Discovery year2008-08-29
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Entrez gene record
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Classification
- Cytoplasmic transfer RNAs
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data