anti-human IL-12/-23 (p40) mAbs MT86/221, purified

• Catalog number
  3450-3-250
• Price
  Please ask
• Size
  250 µg

• Categories
  Antibodies
• Description
  These monoclonal antibodies are specific for the p40 subunit of IL-12 and IL-23. Combine with different detection antibodies for sensitive and specific detection of human IL-12 (p70), IL-12/-23 (p40) and IL-23.
• Recommandation
  We recommend MT86/221 as capture antibodies in ELISA and ELISpot. Combine with mAb MT704 for detection of IL-12 (p70), with mAb MT618 for detection of IL-12/-23 (p40) and with mAb MT155 for detection of IL-23.
• Antibody Clone
  MT86/221
• Enzyme Conjugate
  unconjugated
• Format
  purified
• Application
  ELISpot, ELISA
• Reactivities
  human, non-human primates
• Analytes
  IL12/23 (p40), IL23, IL12 (p70)
• Specificity
  Native and recombinant p40 subunit of IL-12 and IL-23. The antibodies recognize p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
• Contents
  MT86/221, purified, supplied at 0.5 mg/ml in PBS with 0.02% sodium azide
• Datasheet
• Product Header
  Monoclonal antibodies specific for IL-12/-23 (p40)
• GeneID
  The monoclonal antibodies cross-react with the p40 subunit of IL-12 and IL-23 from non-human primates.
• Shelf Life
  18 months
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  Mabtech supplies antibodies that are for research of human proteins.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  IL-12   p40   mAbs   MT86/221  
• Gene symbol
  IFNLR1, PIRC55, PIRC54, PIRC53, PIRC57, PIRC56, SNORD116-12, IGHV3OR16-12, SNORD114-12
• Short name
  anti- IL-12/-23 (p40) mAbs MT86/221, purified
• Technique
  anti-Human, purified, anti-, anti, antibody to, antibodies, antibodies against human proteins, purifications
• Host
  Mouse
• Isotype
  IgG1
• Species
  Human, Humans
• Alternative name
  Antibody tohuman Interleukin-12/-23 (p40) mAbs MT86/221, enriched
• Alternative technique
  pure, antibodies

Gene info

• Identity
  HGNC:18584
• Gene
  IFNLR1
• Long gene name
  interferon lambda receptor 1
• Synonyms gene
  • IL28RA
• Synonyms gene name
  • interleukin 28 receptor, alpha
  • interleukin 28 receptor, alpha (interferon, lambda receptor)
  • interferon, lambda receptor 1
• Synonyms
  • CRF2/12
  • IFNLR
  • IL-28R1
• GenBank acession
  • AY129153
• Locus
  1p36.11
• Discovery year
  2002-12-02
• Entrez gene record
  163702
• RefSeq identity
  • NM_170743
• Classification
  • Interferon receptors
• VEGA ID
  OTTHUMG00000003036

Gene info

• Identity
  HGNC:37559
• Gene
  PIRC55
• Long gene name
  piwi-interacting RNA cluster 55
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313792
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37558
• Gene
  PIRC54
• Long gene name
  piwi-interacting RNA cluster 54
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313815
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37557
• Gene
  PIRC53
• Long gene name
  piwi-interacting RNA cluster 53
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313861
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37561
• Gene
  PIRC57
• Long gene name
  piwi-interacting RNA cluster 57
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313930
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37560
• Gene
  PIRC56
• Long gene name
  piwi-interacting RNA cluster 56
• Locus
  12
• Discovery year
  2009-11-05
• Entrez gene record
  100313862
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33078
• Gene
  SNORD116-12
• Long gene name
  small nucleolar RNA, C/D box 116-12
• Synonyms
  • HBII-85-12
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033424
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003327
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5636
• Gene
  IGHV3OR16-12
• Long gene name
  immunoglobulin heavy variable 3/OR16-12 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-12
• Synonyms
  • IGHV3/OR16-12
• GenBank acession
  • Z29609
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28304
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176355

Gene info

• Identity
  HGNC:33000
• Gene
  SNORD114-12
• Long gene name
  small nucleolar RNA, C/D box 114-12
• Synonyms
  • 14q(II-12)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767590
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003205.1
• Classification
  • Small nucleolar RNAs, C/D box

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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