anti-mouse TNF-alpha mAbs MT1C8/23C9, purified
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Catalog number
3511-3-1000
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Price
Please ask
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Size
1 mg
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Categories
Antibodies
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Description
These monoclonal antibodies enable sensitive and specific detection of mouse TNF-α in immunoassays such as ELISA and ELISpot.
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Recommandation
We recommend MT1C8/23C9 as capture antibodies in ELISA and ELISpot in combination with biotinylated detection antibody MT11B10.
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Antibody Clone
MT1C8/23C9
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Enzyme Conjugate
unconjugated
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Format
purified
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Application
ELISA, ELISpot
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Reactivities
mouse
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Analytes
TNFA
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Specificity
Native and recombinant TNF-α
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Contents
MT1C8/23C9, purified, supplied at 0.5 mg/ml in PBS with 0.02% sodium azide
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Product Header
Monoclonal antibodies specific for TNF-α
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Shelf Life
18 months
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Additional description
The anti-mouse TNF-alpha mAbs MT1C8/23C9, purified is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbol
TNF, TNFRSF1A, TNFRSF1B, LTBR
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Short name
anti-mouse TNF-alpha mAbs MT1C8/23C9, purified
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Technique
purified, anti-, Mouse, anti, antibody to, antibodies, mouses, purifications
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Host
Rat
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Isotype
IgG2a
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Species
Mouse, Mouses
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Alternative name
Antibody tomouse tumor necrosis factor-a mAbs MT1C8/23C9, enriched
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Alternative technique
pure, murine, antibodies
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Alternative to gene target
tumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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