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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
30562-34-6
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Chemical s molecular weight
560.64
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Chemical s main applications
Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines. It binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.
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Chemical s category
Amines, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-Carbamate; (+)-Geldanamycin; NSC 122750; NSC 212518;
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Chemical s formula
C29H40N2O9
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Physical properties
Yellow to Orange Solid
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Melting temperature
236-240˚C
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Boiling temperature
No Data Available
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Chemical s soluble in
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
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Stability conditions
No Data Available
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Storage
-20°C Freezer
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