17-(Allylamino) Geldanamycin
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Catalog number
A549650
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Price
Please ask
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Size
100 µg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
75747-14-7
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Chemical s molecular weight
585.69
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Chemical s main applications
Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
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Chemical s category
Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG
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Chemical s formula
C31H43N3O8
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Physical properties
Dark Purple Solid
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Melting temperature
>194°C (dec.)
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Boiling temperature
No Data Available
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Chemical s soluble in
Chloroform, DMSO, Methanol
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Stability conditions
No Data Available
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Storage
-20°C Freezer, Under Inert Atmosphere
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