Mouse anti alpha SNAP

• Catalog number
  X1025
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  SNAPs (soluble NSF attachment proteins), acting in concert SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or bSNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20 S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process. Whereas a-SNAP is expressed in all mammalian tissues, b-SNAP is expressed only in brain.
• Antibody come from
  Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human a-SNAP protein and mouse myeloma cells.
• Other description
  Provided as sterile filtered solution containing 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol at pH 7.5.
• Clone
  4E4
• Antigen antibody binding interaction
  Mouse anti alpha SNAP Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Rat, Bovine
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot, Immunoprecipitation
• Antibody s suited for
  Antibody can be used for Western blotting (1:5000 dilution) and immunoprecipitation on native and denatured samples. Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  The Mouse anti alpha SNAP is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  alpha   SNAP  
• Gene symbol
  NAPB, SNAP25, SNAP29, SNAP47
• Short name
  Mouse anti alpha SNAP
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to a SNAP
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:15751
• Gene
  NAPB
• Long gene name
  NSF attachment protein beta
• Synonyms gene name
  • N-ethylmaleimide-sensitive factor attachment protein, beta
• Synonyms
  • SNAP-BETA
  • SNAPB
• Synonyms name
  • beta soluble NSF attachment protein
• GenBank acession
  • AK022817
• Locus
  20p11.21
• Discovery year
  2001-05-30
• Entrez gene record
  63908
• Pubmed identfication
  • 8455721
• RefSeq identity
  • NM_022080
• VEGA ID
  OTTHUMG00000032062

Gene info

• Identity
  HGNC:11132
• Gene
  SNAP25
• Long gene name
  synaptosome associated protein 25
• Synonyms gene
  • SNAP
• Synonyms gene name
  • synaptosomal-associated protein, 25kDa
• Synonyms
  • SNAP-25
  • RIC-4
  • RIC4
  • SEC9
  • bA416N4.2
  • dJ1068F16.2
• Synonyms name
  • resistance to inhibitors of cholinesterase 4 homolog
• Locus
  20p12.2
• Discovery year
  1995-01-24
• Entrez gene record
  6616
• Pubmed identfication
  • 8661740
  • 10692432
• RefSeq identity
  • NM_130811
• Classification
  • SNAREs
• VEGA ID
  OTTHUMG00000031863

Gene info

• Identity
  HGNC:11133
• Gene
  SNAP29
• Long gene name
  synaptosome associated protein 29
• Synonyms gene name
  • synaptosomal-associated protein, 29kDa
• Synonyms
  • SNAP-29
  • CEDNIK
• Synonyms name
  • soluble 29 kDa NSF attachment protein
  • cerebral dysgenesis, neuropathy, ichthyosis and keratoderma syndrome
• GenBank acession
  • AF115436
• Locus
  22q11.21
• Discovery year
  1998-12-17
• Entrez gene record
  9342
• Pubmed identfication
  • 9852078
  • 10591208
• RefSeq identity
  • NM_004782
• Classification
  • SNAREs
• VEGA ID
  OTTHUMG00000150765

Gene info

• Identity
  HGNC:30669
• Gene
  SNAP47
• Long gene name
  synaptosome associated protein 47
• Synonyms gene
  • C1orf142
• Synonyms gene name
  • chromosome 1 open reading frame 142
  • synaptosomal-associated protein, 47kDa
• Synonyms
  • SVAP1
  • SNAP-47
• GenBank acession
  • AY090635
• Locus
  1q42.13
• Discovery year
  2005-07-08
• Entrez gene record
  116841
• Pubmed identfication
  • 16621800
• RefSeq identity
  • NM_053052
• VEGA ID
  OTTHUMG00000037697

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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